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Hydroxy group
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==Properties== [[File:Sulfuric-acid-2D-dimensions.svg|thumb|left|[[Sulfuric acid]] contains two hydroxyl groups.]] Water, alcohols, [[carboxylic acids]], and many other hydroxy-containing compounds can be readily [[Deprotonation|deprotonated]] due to a large difference between the electronegativity of oxygen (3.5) and that of hydrogen (2.1). Hydroxy-containing compounds engage in intermolecular [[hydrogen bond]]ing increasing the electrostatic attraction between molecules and thus to higher boiling and melting points than found for compounds that lack this [[functional group]]. Organic compounds, which are often poorly soluble in water, become water-soluble when they contain two or more hydroxyl groups, as illustrated by [[sugar]]s and [[amino acid]].<ref>{{cite web | url=https://www.khanacademy.org/science/organic-chemistry/gen-chem-review/electronegativity-polarity/v/solubility-of-organic-compounds-redo#:~:text=More%20videos%20on%20YouTube&text=Organic%20compounds%20tend%20to%20dissolve,dissolve%20in%20non%2Dpolar%20solvents | title=Khan Academy }}</ref><ref>{{cite web | url=https://chem.libretexts.org/Bookshelves/General_Chemistry/CLUE%3A_Chemistry_Life_the_Universe_and_Everything/06%3A_Solutions/6.3%3A_Hydrogen_Bonding_Interactions_and_Solubility#:~:text=How%20does%20adding%20hydroxyl%20groups,rather%20than%20the%20solvent%20molecules | title=6.3: Hydrogen Bonding Interactions and Solubility | date=11 November 2021 }}</ref>
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