Editing Mefenamic acid (section)

==Medical uses==
Mefenamic acid is used to treat pain and inflammation in [[rheumatoid arthritis]] and [[osteoarthritis]], postoperative pain, acute pain including [[muscle pain|muscle]] and [[back pain]], [[toothache]] and [[dysmenorrhoea|menstrual pain]], as well as being prescribed for [[menorrhagia]].<ref>{{Cite journal|url=https://about.medicinescomplete.com/|title=Digital Medicines Information Suite|website=MedicinesComplete|language=en-GB|doi=10.18578/bnf.855907230|access-date=2020-04-18|url-access=subscription}}</ref><ref name="AustriaCodex" /><ref name="mediQ" /> In a 10-year study, mefenamic acid and other oral medicines ([[tranexamic acid]]) were as effective as the [[Hormonal intrauterine device|levonorgestrel intrauterine coil]]; the same proportion of women had not had surgery for heavy bleeding and had similar improvements in their quality of life.<ref>{{cite journal | vauthors = Kai J, Dutton B, Vinogradova Y, Hilken N, Gupta J, Daniels J | title = Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study | language = EN | journal = Health Technology Assessment | volume = 27 | issue = 17 | pages = 1–50 | date = October 2023 | pmid = 37924269 | pmc = 10641716 | doi = 10.3310/JHSW0174 }}</ref><ref>{{Cite journal |date=8 March 2024 |title=The coil and medicines are both effective long-term treatments for heavy periods |url=https://evidence.nihr.ac.uk/alert/the-coil-and-medicines-are-both-effective-long-term-treatments-for-heavy-periods/ |journal=NIHR Evidence|doi=10.3310/nihrevidence_62335 |url-access=subscription }}</ref>

There is evidence that supports the use of mefenamic acid for perimenstrual [[migraine headache]] prophylaxis, with treatment starting two days prior to the onset of flow or one day prior to the expected onset of the headache and continuing for the duration of [[menstruation]].<ref name=Pringsheim>{{cite journal | vauthors = Pringsheim T, Davenport WJ, Dodick D | title = Acute treatment and prevention of menstrually related migraine headache: evidence-based review | journal = Neurology | volume = 70 | issue = 17 | pages = 1555–1563 | date = April 2008 | pmid = 18427072 | doi = 10.1212/01.wnl.0000310638.54698.36 | s2cid = 27966664 }}</ref>

Mefenamic acid is recommended to be taken with food.<ref>{{ cite web | url = https://www.nlm.nih.gov/medlineplus/druginfo/meds/a681028.html#side-effects | publisher = National Institutes of Health | work = Medline Plus | title = Side effects for Mefenamic Acid }}</ref>