Editing Monoamine neurotransmitter (section)

== Examples ==
{{Catecholamine and trace amine biosynthesis|caption=Phenethylaminergic trace amines and the catecholamines are derivatives of L-phenylalanine.|align=right}}
{{transcluded section|source=Trace amine|part=yes}}
;Classical monoamines
* [[Imidazole]]amines:
** [[Histamine]]<ref name="pmid18989452">{{cite journal |vauthors=Romero-Calderón R, Uhlenbrock G, Borycz J, Simon AF, Grygoruk A, Yee SK, Shyer A, Ackerson LC, Maidment NT, Meinertzhagen IA, Hovemann BT, Krantz DE |title=A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system |journal=PLOS Genet. |volume=4 |issue=11 |pages=e1000245 |date=November 2008  |pmid=18989452 |pmc=2570955 |doi=10.1371/journal.pgen.1000245 |quote=Unlike other monoamine neurotransmitters, the mechanism by which the brain's histamine content is regulated remains unclear. In mammals, vesicular monoamine transporters (VMATs) are expressed exclusively in neurons and mediate the storage of histamine and other monoamines. |doi-access=free }}</ref>
* [[Catecholamine]]s:
** [[Adrenaline]] (Ad; Epinephrine, Epi)
** [[Dopamine]] (DA)
** [[Noradrenaline]] (NAd; Norepinephrine, NE)
* [[Indolamines]]:
**[[Serotonin]] (5-HT)
**[[Melatonin]] (MT)

;Trace amines:
{{trim|{{:Trace amine}}}}

Specific transporter [[protein]]s called [[monoamine transporter]]s that transport monoamines in or out of a cell exist. These are the [[dopamine transporter]] (DAT), [[serotonin transporter]] (SERT), and the [[norepinephrine transporter]] (NET) in the outer [[cell membrane]] and the [[vesicular monoamine transporter]] ([[VMAT1]] and [[VMAT2]]) in the membrane of intracellular [[vesicle (biology)|vesicle]]s.{{citation needed|date=April 2013}}

After release into the [[synaptic cleft]], monoamine neurotransmitter action is ended by reuptake into the presynaptic terminal.  There, they can be repackaged into synaptic vesicles or degraded by the [[enzyme]] [[monoamine oxidase]] (MAO), which is a target of [[monoamine oxidase inhibitors]], a class of [[antidepressants]].{{citation needed|date=April 2013}}