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Neomycin
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==Discovery== Neomycin was discovered in 1949 by the microbiologist [[Selman Waksman]] and his student Hubert Lechevalier at [[Rutgers University]]. It is produced naturally by the bacterium ''[[Streptomyces fradiae]]''.<ref>{{cite web|url=http://nobelprize.org/nobel_prizes/medicine/laureates/1952/waksman-bio.html|title=The Nobel Prize in Physiology or Medicine 1952|publisher=Nobel Foundation|access-date=2008-10-29|archive-date=2018-06-19|archive-url=https://web.archive.org/web/20180619213821/https://www.nobelprize.org/nobel_prizes/medicine/laureates/1952/waksman-bio.html|url-status=live}}</ref> Synthesis requires specific nutrient conditions in either stationary or submerged aerobic conditions. The compound is then isolated and purified from the bacterium.<ref>{{cite book | chapter = Neomycin | title = Pharmaceutical Manufacturing Encyclopedia | edition = 3rd | volume = 3 | date = 2007 | pages = 2415β2416 }}</ref>
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