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Nocebo
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==Etymology and usage== Walter Kennedy coined the term ''nocebo'' ([[Latin language|Latin]] {{Wikt-lang|la|nocēbō}}, "I shall harm", from {{Wikt-lang|la|noceō}}, "I harm")<ref>{{cite dictionary|url=http://www.merriam-webster.com/dictionary/nocebo|dictionary=[[Merriam-Webster]]|title=Merriam-Webster Online Dictionary}} {{L&S|noceo|ref}}</ref> in 1961 to denote the counterpart of ''placebo'' (Latin {{Wikt-lang|la|placēbō}}, "I shall please", from {{Wikt-lang|la|placeō}}, "I please"),<ref>{{OEtymD|placebo}} {{L&S|placeo|ref}}</ref> a substance that may produce a beneficial, healthful, pleasant, or desirable effect. Kennedy emphasized that his use of the term ''nocebo'' refers strictly to a subject-centered response, a quality "inherent in the patient rather than in the remedy".{{sfn|Kennedy|1961}} That is, he rejected the use of the term for [[Pharmacology|pharmacologically]] induced negative [[Adverse effect (medicine)|side effects]] such as the [[ringing in the ears]] caused by [[quinine]].{{sfn|Kennedy|1961}} That is not to say that the patient's psychologically induced response may not include physiological effects. For example, an expectation of pain may induce anxiety, which in turn causes the release of [[cholecystokinin]], which facilitates pain transmission.{{sfn|Benedetti|Lanotte|Lopiano|Colloca|2007}}
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