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Orthostatic hypotension
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==Anatomy and physiology== To maintain sufficient blood pressure, the body has several compensatory mechanisms. [[Baroreceptor|Baroreceptors]], a kind of mechanoreceptors, play a crucial role in conveying data about blood pressure in the autonomic nervous system. The data is conveyed to regulate the peripheral resistance and heart output, keeping blood pressure within an established normal limit.<ref name="Bradley2003">{{cite journal |last1=Bradley |first1=JG |last2=Davis |first2=KA |title=Orthostatic hypotension. |journal=American Family Physician |date=15 December 2003 |volume=68 |issue=12 |pages=2393β8 |pmid=14705758}}</ref> There are two kinds of baroreceptors: high-pressure arterial baroreceptors and low-pressure volume receptors, both activated by the stretching of vessel walls.<ref name="Bradley2003" /> Arterial baroreceptors are situated in the carotid sinuses and the aortic arch, while the low-pressure volume receptors, known as cardiopulmonary receptors, are in the atria, ventricles, and pulmonary vasculature.<ref name="Bradley2003" /> Arterial baroreceptors detect changes in blood pressure and transmit this information to the brainstem, the nucleus of the solitary tract, which modulates the activity of the autonomic nervous system (ANS).<ref name="Ringer2024">{{cite journal |last1=Ringer |first1=Matthew |last2=Lappin |first2=Sarah L. |title=Orthostatic Hypotension |journal=StatPearls |date=2024 |url=https://www.ncbi.nlm.nih.gov/books/NBK448192/ |publisher=StatPearls Publishing|pmid=28846238 }}</ref> This results in decreased blood pressure, which leads to an increase in heart rate.<ref name="Ringer2024" /> What's more, the venoarteriolar axon reflex, which results in the constriction of arterial flow to muscles, skin, and adipose tissue also helps stabilize blood pressure.<ref name="Ringer2024" />
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