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Overwhelming post-splenectomy infection
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== Signs and symptoms == OPSI may initially present with [[Influenza-like illness|mild viral symptoms]] such as fever or coughing, however later in infection symptoms may include shakes, [[Shivering|shivers]], [[chills]], [[diarrhea]], [[vomiting]], [[malaise]], [[myalgia]], [[headache]] and [[abdominal pain]].<ref name="Luu2019" /><ref name=":0">{{Cite journal|last1=Taniguchi|first1=Leandro Utino|last2=Correia|first2=MΓ‘rio Diego Teles|last3=Zampieri|first3=Fernando Godinho|date=December 2014|title=Overwhelming post-splenectomy infection: narrative review of the literature|url=https://pubmed.ncbi.nlm.nih.gov/25318011/|journal=Surgical Infections|volume=15|issue=6|pages=686β693|doi=10.1089/sur.2013.051|issn=1557-8674|pmid=25318011}}</ref> The disease progresses rapidly from the above mentioned symptoms to [[coma]] to refractory [[septic shock]] and finally death in as little as 24 hours.<ref name=":0" />
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