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Partition coefficient
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== Nomenclature == Despite formal recommendation to the contrary, the term ''partition coefficient'' remains the predominantly used term in the scientific literature.<ref name="McAuley_2013">{{cite book | vauthors = McAuley W | chapter = Hydrophobicity and Partitioning | chapter-url = https://books.google.com/books?id=lZGcAQAAQBAJ&pg=PT144 | veditors = Denton P, Rostron C | title = Pharmaceutics: The Science of Medicine Design | date = 2013 | isbn = 978-0-19-965531-1 | page = 129 | publisher = OUP Oxford }}</ref>{{additional citation needed|date=March 2016}} <!--More examples than one are needed for this far-reaching statement. Best, if we can supply a source where someone actually says this very thing. In terms of collecting examples, the two physical pharmacy sources recently linked in Talk could supply two more sources.--> In contrast, the [[IUPAC]] recommends that the title term no longer be used, rather, that it be replaced with more specific terms.<ref name="isbn0-86542-684-8"/> For example, ''partition constant'', defined as {{NumBlk|:|{{math|1= (''K''<sub>D</sub>)<sub>A</sub> = {{sfrac|[A]<sub>org</sub> | [A]<sub>aq</sub>}}}},|{{EquationRef|1}}}} where ''K''<sub>D</sub> is the process [[equilibrium constant]], [A] represents the concentration of solute A being tested, and "org" and "aq" refer to the organic and aqueous phases respectively. The IUPAC further recommends "partition ratio" for cases where [[chemical activity|transfer activity coefficients]] can be determined, and "distribution ratio" for the ratio of total analytical concentrations of a solute between phases, regardless of chemical form.<ref name="isbn0-86542-684-8">{{cite book | vauthors = Wilkinson AM, McNaught AD | veditors = Miloslav N, Jirát J, Košata B, Jenkins A, McNaught A | title = Compendium of Chemical Terminology: IUPAC Recommendations | publisher = Blackwell Science | location = Oxford | year = 1997 | isbn = 978-0-86542-684-9 | doi = 10.1351/goldbook | chapter = Partition Coefficient | chapter-url = http://goldbook.iupac.org/P04437.html }}</ref>
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