Editing Primordial soup (section)

==Historical background ==
The notion that living beings originated from inanimate materials comes from the Ancient Greeks—the theory known as [[spontaneous generation]]. [[Aristotle]] in the 4th century BCE gave a proper explanation, writing:

{{blockquote|So with animals, some spring from parent animals according to their kind, whilst others grow spontaneously and not from kindred stock; and of these instances of spontaneous generation some come from putrefying earth or vegetable matter, as is the case with a number of insects, while others are spontaneously generated in the inside of animals out of the secretions of their several organs.<ref name="HistAnimV">{{cite book |author=Aristotle |author-link=Aristotle |others=translated by D'Arcy Wentworth Thompson |title=The History of Animals |url=https://ebooks.adelaide.edu.au/a/aristotle/history/complete.html |access-date=2008-12-20 |orig-year=c. 343 BCE |year=1910 |publisher=Clarendon Press |location=Oxford |chapter=Book V |chapter-url=http://ebooks.adelaide.edu.au/a/aristotle/history/book5.html |isbn=90-6186-973-0 |archive-date=2018-05-08 |archive-url=https://web.archive.org/web/20180508025913/https://ebooks.adelaide.edu.au/a/aristotle/history/ |url-status=dead }}</ref> |Aristotle |''On the History of Animals'', Book V, Part 1}}
Aristotle also states that it is not only that animals originate from other similar animals, but also that living things do arise and always have arisen from lifeless matter. His theory remained the dominant idea on origin of life (outside that of deity as a causal agent) from the ancient philosophers to the [[Renaissance]] thinkers in various forms.<ref>{{cite book |url=https://books.google.com/books?id=5oQ_SQAACAAJ |title=Historical Encyclopedia of Natural and Mathematical Sciences |last1=Ben-Menahem |first1=Ari |date=2009 |publisher=Springer |isbn=978-3-540-68834-1 |edition=1st |location=Berlin |pages=270–280 |chapter=The Spontaneous Generation Controversy |access-date=2020-10-10 |archive-date=2022-04-26 |archive-url=https://web.archive.org/web/20220426234243/https://books.google.com/books?id=5oQ_SQAACAAJ |url-status=live }}</ref> With the birth of modern science, experimental refutations emerged. Italian physician [[Francesco Redi]] demonstrated in 1668 that [[maggots]] developed from rotten meat only in a jar where flies could enter, but not in a closed-lid jar. He concluded that: ''omne vivum ex vivo'' (All life comes from life).<ref>{{cite journal |last1=Gottdenker |first1=P. |date=1979 |title=Francesco Redi and the fly experiments |journal=Bulletin of the History of Medicine |volume=53 |issue=4 |pages=575–592 |pmid=397843}}</ref>

The experiment of French chemist [[Louis Pasteur]] in 1859 is regarded as the death blow to spontaneous generation. He experimentally showed that organisms (microbes) can not grow in sterilised water, unless it is exposed to air. The experiment won him the Alhumbert Prize in 1862 from the [[French Academy of Sciences]], and he concluded: "Never will the doctrine of spontaneous generation recover from the mortal blow of this simple experiment."<ref>{{cite journal |last1=Schwartz |first1=M. |date=2001 |title=The life and works of Louis Pasteur |journal=[[Journal of Applied Microbiology]] |volume=91 |issue=4 |pages=597–601 |doi=10.1046/j.1365-2672.2001.01495.x |pmid=11576293 |s2cid=39020116 |doi-access=}}</ref>

Evolutionary biologists believed that a kind of spontaneous generation, but different from the simple Aristotelian doctrine, must have worked for the emergence of life. French biologist [[Jean-Baptiste de Lamarck]] had speculated that the first life form started from non-living materials. "Nature, by means of heat, light, electricity and moisture", he wrote in 1809 in ''[[Philosophie Zoologique]]'' (''The Philosophy of Zoology''), "forms direct or spontaneous generation at that extremity of each kingdom of living bodies, where the simplest of these bodies are found".<ref name="lazcano10" />

When English naturalist [[Charles Darwin]] introduced the theory of [[natural selection]] in his 1859 book ''[[On the Origin of Species]]'', his supporters, such as the German zoologist [[Ernst Haeckel]], criticised him for not using his theory to explain the origin of life. Haeckel wrote in 1862: "The chief defect of the Darwinian theory is that it throws no light on the origin of the primitive organism—probably a simple cell—from which all the others have descended. When Darwin assumes a special creative act for this first species, he is not consistent, and, I think, not quite sincere."<ref>{{cite book |url=https://books.google.com/books?id=P9AoDwAAQBAJ |title=What is Life? On Earth and Beyond |last=Losch |first=Andreas |date=2017 |publisher=Cambridge University Press |isbn=978-1-107-17589-1 |location=Cambridge |page=79 |access-date=2020-10-10 |archive-date=2022-04-26 |archive-url=https://web.archive.org/web/20220426234243/https://books.google.com/books?id=P9AoDwAAQBAJ |url-status=live }}</ref>

Although Darwin did not speak explicitly about the origin of life in ''On the Origin of Species'', he did mention a "warm little pond" in a letter to [[Joseph Dalton Hooker]] dated February 1, 1871:<ref name="pereto">{{cite journal |last1=Peretó |first1=Juli |last2=Bada |first2=Jeffrey L. |last3=Lazcano |first3=Antonio |title=Charles Darwin and the Origin of Life |journal=Origins of Life and Evolution of Biospheres |date=2009 |volume=39 |issue=5 |pages=395–406 |doi=10.1007/s11084-009-9172-7 |pmid=19633921 |pmc=2745620}}</ref>

{{blockquote|text=It is often said that all the conditions for the first production of a living being are now present, which could ever have been present. But if (and oh what a big if) we could conceive in some warm little pond with all sort of ammonia and phosphoric salts,—light, heat, electricity present, that a protein compound was chemically formed, ready to undergo still more complex changes, at the present such matter would be instantly devoured, or absorbed, which would not have been the case before living creatures were formed [...]. |sign=Charles Darwin |source=Letter to Joseph Dalton Hooker on February 1, 1871}}

===Heterotrophic theory===

A coherent scientific argument was introduced by [[Soviet Union|Soviet]] biochemist Alexander Oparin in 1924. According to Oparin, in the primitive Earth's surface, [[carbon]], [[hydrogen]], water vapour, and [[ammonia]] reacted to form the first organic compounds. Unbeknownst to Oparin, whose writing was circulated only in Russian, an [[English people|English]] scientist [[J. B. S. Haldane]] independently arrived at a similar conclusion in 1929.<ref name="Oparin">{{Cite web |url=http://breadtagsagas.com/wp-content/uploads/2015/12/AI-Oparin-The-Origin-of-Life.pdf |title=The Origin of Life |last=Oparin |first=Alexander |access-date=2018-10-24 |archive-date=2018-08-22 |archive-url=https://web.archive.org/web/20180822014725/http://breadtagsagas.com/wp-content/uploads/2015/12/AI-Oparin-The-Origin-of-Life.pdf |url-status=live }}</ref><ref>{{Cite web |url=http://www.uv.es/~orilife/textos/Haldane.pdf |title=The Origin of Life |last=Haldane |first=John B. S. |access-date=2018-10-24 |archive-date=2003-09-27 |archive-url=https://web.archive.org/web/20030927095824/http://www.uv.es/~orilife/textos/Haldane.pdf |url-status=live }}</ref> It was Haldane who first used the term "soup" to describe the accumulation of organic material and water in the primitive Earth<ref name=":0" /><ref name="lazcano10">{{cite journal |last1=Lazcano |first1=A. |title=Historical Development of Origins Research |journal=Cold Spring Harbor Perspectives in Biology |date=2010 |volume=2 |issue=11 |pages=a002089 |doi=10.1101/cshperspect.a002089 |pmid=20534710 |pmc=2964185}}</ref>

{{Blockquote |text=When ultra-violet light acts on a mixture of water, [[carbon dioxide]], and ammonia, a vast variety of organic substances are made, including sugars and apparently some of the materials from which proteins are built up. [...] before the origin of life they must have accumulated till the primitive oceans reached the consistency of hot dilute soup. |sign=J. B. S. Haldane |source=The Origin of Life}}

According to the theory, organic compounds essential for life forms were synthesized in the primitive Earth under prebiotic conditions. The mixture of inorganic and organic compounds with water on the primitive Earth became the prebiotic or primordial soup. There, life originated and the first forms of life were able to use the organic molecules to survive and reproduce. Today the theory is variously known as the heterotrophic theory, heterotrophic origin of life theory, or the Oparin-Haldane hypothesis.<ref name="fry">{{cite journal |last=Fry |first=Iris |title=The origins of research into the origins of life |journal=Endeavour |date=2006 |volume=30 |issue=1 |pages=24–28 |doi=10.1016/j.endeavour.2005.12.002 |pmid=16469383}}</ref> Biochemist [[Robert Shapiro (chemist)|Robert Shapiro]] has summarized the basic points of the theory in its "mature form" as follows:<ref>{{cite book |last=Shapiro |first=Robert |title=Origins: A Skeptic's Guide to the Creation of Life on Earth |publisher=Bantam Books |year=1987 |page=[https://archive.org/details/originsskepticsg0000shap/page/110 110] |isbn=0-671-45939-2 |url=https://archive.org/details/originsskepticsg0000shap/page/110 }}</ref>

# Early Earth had a chemically [[reducing atmosphere]].
# This atmosphere, exposed to energy in various forms, produced simple organic compounds ("[[monomer]]s").
# These compounds accumulated in the prebiotic soup, which may have been concentrated at places such as shorelines and [[Hydrothermal vent|oceanic vents]].
# By further transformation, more complex organic [[polymer]]s – and ultimately life – developed in the soup.