Editing Proline (section)

==History and etymology==
Proline was first isolated in 1900 by [[Richard Willstätter]] who obtained the amino acid while studying ''N''-methylproline, and synthesized proline by the reaction of sodium salt of [[diethyl malonate]] with [[1,3-dibromopropane]]. The next year, [[Emil Fischer]] isolated proline from [[casein]] and the decomposition products of γ-phthalimido-propylmalonic ester,<ref>{{Citation | vauthors = Plimmer RH |author-link=R. H. A. Plimmer | veditors = Plimmer RH, Hopkins FG |title= The chemical composition of the proteins |url= https://books.google.com/books?id=7JM8AAAAIAAJ&pg=PA130 |access-date= September 20, 2010 |edition= 2nd |series= Monographs on biochemistry |volume= Part I. Analysis |orig-year= 1908 |year= 1912 |publisher= Longmans, Green and Co. |location= London|page= 130}}</ref> and published the synthesis of proline from phthalimide propylmalonic ester.<ref>{{cite web|title=Proline|url=http://www.aminoacidsguide.com/Pro.html|url-status=live|archive-url=https://web.archive.org/web/20151127055301/http://www.aminoacidsguide.com/Pro.html|archive-date=2015-11-27 | work = Amino Acids Guide }}</ref>

The name proline comes from [[pyrrolidine]], one of its constituents.<ref>{{cite web |url=http://www.yourdictionary.com/proline |title=Proline |work=American Heritage Dictionary of the English Language, 4th edition |access-date=2015-12-06 |url-status=live |archive-url=https://web.archive.org/web/20150915121147/http://www.yourdictionary.com/proline |archive-date=2015-09-15 }}</ref>