Editing Promethazine (section)

==Medical uses==
Promethazine has a variety of medical uses, including:

* Sedation<ref name=Promethazinestats/>
* In Germany, it is approved for the treatment of agitation and agitation associated with underlying psychiatric disorders with a maximum daily dose of 200 mg.<ref>{{Cite web |title=Promethazin - Anwendung, Wirkung, Nebenwirkungen {{!}} Gelbe Liste |url=https://www.gelbe-liste.de/wirkstoffe/Promethazin_22041 |access-date=22 May 2023 |website=Gelbe Liste Online |language=de | vauthors = Online GL }}</ref>
* For nausea and vomiting associated with anesthesia or chemotherapy. It is commonly used postoperatively as an [[antiemetic]]. The antiemetic activity increases with increased dosing; however, side effects also increase, which often limits maximal dosing.<ref name=Promethazinestats/>
* For moderate to severe [[morning sickness]] and [[hyperemesis gravidarum]]: In the [[UK]], Promethazine is the [[drug]] of first choice. Promethazine is preferred during pregnancy because it is an older drug and there is more data regarding the use of it during [[pregnancy]]. Second-choice medications, which are used if Promethazine isn't tolerated or the patient cannot take it, are [[metoclopramide]] or [[prochlorperazine]].<ref name="BNF">{{cite book | author=British National Formulary | title=BNF | edition=45 |date=March 2001 | chapter=4.6 Drugs used in nausea and Vertigo - Vomiting of pregnancy}}.</ref><ref name=Promethazinestats>{{cite journal |vauthors=Southard BT, Al Khalili Y|title=Promethazine |date=2019 |journal=StatPearls|pmid=31335081}}{{CC-notice|by4}}</ref>
* For allergies such as [[hay fever]] and together with other medications in [[anaphylaxis]]<ref name=AHFS2018/>
* To aid with symptoms of the [[common cold]]<ref name=AHFS2018/>
* [[Motion sickness]],<ref name=AHFS2018/> including [[space adaptation syndrome|space sickness]]<ref>{{cite web |title=Rhea Seddon Oral History |url=https://historycollection.jsc.nasa.gov/JSCHistoryPortal/history/oral_histories/SeddonMR/SeddonMR_5-10-11.htm |website=NASA Johnson Space Center Oral History Project |access-date=25 May 2021 |date=10 May 2011}}</ref>
* [[Hemolytic disease of the newborn]]<ref name=AHFS2018/>
* [[Anxiety]] before surgery<ref name=AHFS2018/>
* Short-term [[insomnia]]<ref name="nhs-Promethazine">{{cite web |title=Promethazine (Phenergan) |url=https://www.nhs.uk/medicines/Promethazine/ |website=Medicines A to Z |publisher=[[National Health Service]] |access-date=2 October 2023 |archive-url=https://web.archive.org/web/20230803160343/https://www.nhs.uk/medicines/Promethazine/ |archive-date=3 August 2023 |date=27 October 2021 |url-status=live}}</ref>