Editing Protein tertiary structure (section)

== History ==
The science of the tertiary structure of proteins has progressed from one of [[hypothesis]] to one of detailed definition. Although [[Hermann Emil Fischer|Emil Fischer]] had suggested proteins were made of [[polypeptide chain]]s and amino acid side chains, it was [[Dorothy Maud Wrinch]] who incorporated [[geometry]] into the prediction of [[protein structure]]s. Wrinch demonstrated this with the [[Cyclol|''Cyclol'' model]], the first prediction of the structure of a [[globular protein]].<ref>Senechal M. [https://books.google.com/books?id=KE0k-reQCP8C&q=dorothy+wrinch "I died for beauty: Dorothy Wrinch and the cultures of science."] Oxford University Press, 2012. Chapter 14. {{ISBN|0-19-991083-9}}, 9780199910830. Accessed at Google Books 8 December 2013.</ref> Contemporary methods are able to determine, without prediction, tertiary structures to within 5 [[Angstrom|Å]] (0.5&nbsp;nm) for small proteins (<120 residues) and, under favorable conditions, confident [[secondary structure]] predictions.