Editing Quorum sensing (section)

==Discovery==
The first observations of an autoinducer-controlled phenotype in bacteria were reported in 1970, by Kenneth Nealson, Terry Platt, and [[J. Woodland Hastings]],<ref name="Nealson-et-al-1970">{{cite journal | vauthors = Nealson KH, Platt T, Hastings JW | title = Cellular control of the synthesis and activity of the bacterial luminescent system | journal = Journal of Bacteriology | volume = 104 | issue = 1 | pages = 313–322 | date = October 1970 | pmid = 5473898 | pmc = 248216 | doi = 10.1128/jb.104.1.313-322.1970 }}</ref> who observed what they described as a conditioning of the medium in which they had grown the [[bioluminescent]] marine bacterium ''[[Aliivibrio fischeri]]''.<ref name="Bodman-et-al-2003" /> These bacteria did not synthesize [[luciferase]]—and therefore did not luminesce—in freshly inoculated culture but only after the bacterial population had increased significantly.

In a series of publications from 1998 to 2001, [[Bonnie Bassler]] showed that quorum sensing is not just an isolated mechanism in ''[[Aliivibrio fischeri]]'', but is used ubiquitously across bacteria to communicate.<ref>{{Cite journal |last=Bassler |first=Bonnie L |date=1999-12-01 |title=How bacteria talk to each other: regulation of gene expression by quorum sensing |url=https://www.sciencedirect.com/science/article/abs/pii/S1369527499000259 |journal=Current Opinion in Microbiology |volume=2 |issue=6 |pages=582–587 |doi=10.1016/S1369-5274(99)00025-9 |pmid=10607620 |issn=1369-5274|url-access=subscription }}</ref><ref>{{Cite journal |last1=Surette |first1=Michael G. |last2=Bassler |first2=Bonnie L. |date=1998-06-09 |title=Quorum sensing in Escherichia coli and Salmonella typhimurium |journal=Proceedings of the National Academy of Sciences |volume=95 |issue=12 |pages=7046–7050 |doi=10.1073/pnas.95.12.7046 |doi-access=free |pmc=22733 |pmid=9618536|bibcode=1998PNAS...95.7046S }}</ref> This advance demonstrated that bacteria are capable of carrying out complex, collective behaviors.<ref>{{Cite web |title=Tapping into Bacterial Conversations {{!}} HHMI |url=https://www.hhmi.org/news/tapping-bacterial-conversations |access-date=2025-01-31 |website=www.hhmi.org |language=en}}</ref><ref>{{Cite web |date=2009-04-08 |title=The secret, social lives of bacteria: Exclusive interview with Bonnie Bassler {{!}} TED Blog |url=https://blog.ted.com/the_secret_soci/ |access-date=2025-01-31 |language=en-US}}</ref>