Editing Reverse-transcriptase inhibitor (section)

==Mechanism of action==
When HIV infects a cell, reverse transcriptase copies the viral single stranded [[RNA]] genome into a double-stranded viral [[DNA]]. The viral DNA is then integrated into the host chromosomal DNA, which then allows host cellular processes, such as transcription and translation, to reproduce the virus. RTIs block reverse transcriptase's enzymatic function and prevent completion of synthesis of the double-stranded viral DNA, thus preventing HIV from multiplying.{{cn|date=November 2022}}

A similar process occurs with other types of viruses. The hepatitis B virus, for example, carries its genetic material in the form of DNA, and employs an RNA-dependent DNA polymerase to replicate. Some of the same compounds used as RTIs can also block HBV replication; when used in this way they are referred to as polymerase inhibitors.{{cn|date=November 2022}}