Editing Schmorl's nodes (section)

==Signs and symptoms==
These are protrusions of disc material into the surface of the vertebral body, which may contact the [[Bone marrow|marrow]] of the vertebra and lead to [[inflammation]]. The protrusions are also associated with [[necrosis]] of the vertebral bone and the question of whether these protrusions and inflammation cause the necrosis, or whether the cartilage migrates into areas that have become necrotic due to other conditions, is under investigation.{{citation needed|date=September 2021}}

They may or may not be symptomatic, and their link to [[back pain]] is controversial. Williams and colleagues  note that this relationship may be due to [[lumbar disc disease]], as the two commonly occur simultaneously.<ref name="Williams">{{cite journal |doi=10.1002/art.22789 |pmid=17530687 |title=Schmorl's nodes: Common, highly heritable, and related to lumbar disc disease |journal=Arthritis & Rheumatism |volume=57 |issue=5 |pages=855–860 |year=2007 |last1=Williams |first1=F. M. K. |last2=Manek |first2=N. J. |last3=Sambrook |first3=P. N. |last4=Spector |first4=T. D. |last5=MacGregor |first5=A. J. |doi-access=free }}</ref>