Editing Simeticone (section)

==Medical uses==
[[File:Simethiconetablets.jpg|thumb|Simethicone tablets]]
Simeticone is used to relieve the symptoms of excessive gas in the [[gastrointestinal tract]], namely bloating, burping, and flatulence.<ref name=USOTClabel>{{cite web|title=Simethicone tablet|url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d93ff75d-9cdb-476c-bb65-eabeefb91a34|publisher=NIH DailyMed|access-date=27 August 2017|date=April 2016}}</ref><ref>{{cite web|title=Simeticone|url=https://www.nhs.uk/medicines/simeticone/|publisher=[[NHS]]|language=en|date=10 October 2019|access-date=30 January 2020}}</ref> While there is a lack of conclusive evidence that simeticone is effective for this use,⁣<ref>{{cite web| vauthors = Modi R, Clearfield HR, Levitt M | title=Belching, Bloating and Flatulence|url=http://patients.gi.org/topics/belching-bloating-and-flatulence/|publisher=American College of Gastroenterology|language=en|date=July 2013}}</ref><ref name="drugs.com">{{Cite web | url = https://www.drugs.com/monograph/simethicone.html | title = Simethicone | publisher = [[drugs.com]] | quote = Efficacy not established for the symptomatic relief of immediate postprandial upper abdominal distress}}</ref>{{Failed verification|date=January 2020|reason=Flatulence/bloating and IPPUAD are separate sections in source}} studies have shown that it can relieve symptoms of [[functional dyspepsia]]<ref>{{cite journal | vauthors = Holtmann G, Gschossmann J, Mayr P, Talley NJ | title = A randomized placebo-controlled trial of simethicone and cisapride for the treatment of patients with functional dyspepsia | journal = Alimentary Pharmacology & Therapeutics | volume = 16 | issue = 9 | pages = 1641–8 | date = September 2002 | pmid = 12197843 | doi = 10.1046/j.1365-2036.2002.01322.x | publisher = Wiley | s2cid = 23286985 | doi-access =  }}</ref> and [[bloating|functional bloating]].<ref>{{cite journal | vauthors = Burta O, Iacobescu C, Mateescu RB, Nicolaie T, Tiuca N, Pop CS | title = Efficacy and safety of APT036 versus simethicone in the treatment of functional bloating: a multicentre, randomised, double-blind, parallel group, clinical study | journal = Translational Gastroenterology and Hepatology | volume = 3 | issue = 72 | pages = 72 | date = 25 September 2018 | pmid = 30511026 | pmc = 6256934 | doi = 10.21037/tgh.2018.09.11 | publisher = AME Publications | doi-access = free }}</ref>

It has not been fully established that simeticone is useful to treat [[Baby colic|colic]] in babies,<ref>{{cite journal | vauthors = Biagioli E, Tarasco V, Lingua C, Moja L, Savino F | title = Pain-relieving agents for infantile colic | journal = The Cochrane Database of Systematic Reviews | volume = 2016 | pages = CD009999 | date = September 2016 | issue = 9 | pmid = 27631535 | pmc = 6457752 | doi = 10.1002/14651858.CD009999.pub2 }}</ref> and it is not recommended for this purpose.<ref name="drugs.com"/> A study in the United Kingdom reported that according to parental perception simeticone helped infant colic in some cases.<ref>{{cite journal | vauthors = Goldman M, Beaumont T | title = A real world evaluation of a treatment for infant colic based on the experience and perceptions of 4004 parents | journal = British Journal of Nursing | volume = 26 | issue = 5 Suppl 1 | pages = S3–S10 | date = March 2017 | pmid = 28350192 | doi = 10.12968/bjon.2017.26.Sup5.S3 | s2cid = 32885530 }}</ref>

Simeticone can also be used for suspected [[postoperative]] [[abdominal discomfort]] in infants.<ref>{{cite journal | vauthors = Voepel-Lewis TD, Malviya S, Burke C, D'Agostino R, Hadden SM, Siewert M, Tait AR | title = Evaluation of simethicone for the treatment of postoperative abdominal discomfort in infants | journal = Journal of Clinical Anesthesia | volume = 10 | issue = 2 | pages = 91–94 | date = March 1998 | pmid = 9524891 | doi = 10.1016/S0952-8180(97)00249-3 }}</ref>