Editing Synaptic plasticity (section)

==Historical discoveries==
In 1973, [[Terje Lømo]] and [[Tim Bliss]] first described the now widely studied phenomenon of [[long-term potentiation]] (LTP) in a publication in the ''Journal of Physiology''. The experiment described was conducted on the synapse between the [[perforant path]] and [[dentate gyrus]] in the [[Hippocampus|hippocampi]] of anaesthetised rabbits. They were able to show a burst of tetanic (100&nbsp;Hz) stimulus on perforant path fibres led to a dramatic and long-lasting augmentation in the post-synaptic response of cells onto which these fibres synapse in the dentate gyrus. In the same year, the pair published very similar data recorded from awake rabbits. This discovery was of particular interest due to the proposed role of the hippocampus in certain forms of memory.