Editing Transversion (section)

== Ratio of transitions to transversions ==
Although there are two possible transversions but only one possible [[transition (genetics)|transition]] per base, transition mutations are more likely than transversions because substituting a single ring structure for another single ring structure is more likely than substituting a double ring for a single ring. Also, transitions are less likely to result in amino acid substitutions (due to [[wobble base pair]]), and are therefore more likely to persist as "silent substitutions" in populations as [[single nucleotide polymorphism]]s (SNPs).<ref>[https://www.mun.ca/biology/scarr/Transitions_vs_Transversions.html Diagram at mun.ca]</ref> A transversion usually has a more pronounced effect than a transition  because the second and third nucleotide [[codon]] position of the [[DNA]], which to a large extent is responsible for the [[Degeneracy (biology)|degeneracy]] of the [[Genetic code|code]], is more tolerant of transition than a transversion: transitions are more likely to be [[Synonymous substitution|synonymous substitutions]] than transversions, as one observes in the [[DNA and RNA codon tables|codon table]].