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Zolmitriptan
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==Medical uses == ===Migraine=== Zolmitriptan is used for the acute treatment of [[migraine]]s with or without [[aura (symptom)|aura]] in adults.<ref name="Zolmig-Label" /> It is not intended for the [[prophylaxis|prophylactic]] therapy of migraine or for use in the management of [[hemiplegic migraine|hemiplegic]] or [[basilar migraine]].<ref name="Zolmig-Label" /> ===Off-label uses=== * Acute treatment of [[cluster headache]]sβLevel A recommendation from the American Academy of Neurology<ref name=statspe>{{cite journal | vauthors = Abram JA, Patel P | title = Zolmitriptan | journal = Statpearls| date = 2020 | pmid = 32491581}}[[File:CC-BY icon.svg|50px]] Text was copied from this source, which is available under a [https://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International License].</ref> * Acute treatment of [[menstrual migraine]]<ref name=statspe/> ===Available forms=== Zolmitriptan is available as a [[swallowing|swallowed]] [[tablet (pharmacy)|tablet]], an [[orally disintegrating tablet]], and as a [[nasal spray]], in doses of 2.5 and 5{{nbsp}}mg. People who get migraines from [[aspartame]] should not use the disintegrating tablet (Zomig ZMT) as it contains aspartame.<ref>{{cite journal | journal = Headache: The Journal of Head and Face Pain | year = 2001 | volume = 41 | issue =9 | pages = 899β901 | doi= 10.1046/j.1526-4610.2001.01164.x | title =Migraine MLT-Down: An Unusual Presentation of Migraine in Patients With Aspartame-Triggered Headaches |vauthors=Newman LC, Lipton RB | doi-broken-date = 9 December 2024 | pmid = 11703479 | type =abstract}}</ref> A 2014 [[Cochrane review]] has shown that zolmitriptan 5{{nbsp}}mg nasal spray was significantly more effective than the 5{{nbsp}}mg oral tablet.<ref name="BirdDerryMoore2014">{{cite journal |vauthors=Bird S, Derry S, Moore RA |title=Zolmitriptan for acute migraine attacks in adults |journal=Cochrane Database Syst Rev |issue=5 |pages=CD008616 |date=May 2014 |volume=2014 |pmid=24848613 |pmc=6485805 |doi=10.1002/14651858.CD008616.pub2 }}</ref>
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