Editing Axolotl (section)

=== Research history ===
Six adult axolotls (including a leucistic specimen) were shipped from [[Mexico City]] to the ''[[Jardin des Plantes]]'' in Paris in 1863. Unaware of their neoteny, [[Auguste Duméril]] was surprised when, instead of the axolotl, he found in the vivarium a new species, similar to the salamander.{{verify source|reason=French language verification needed|date=November 2021}} This discovery was the starting point of research about neoteny. It is not certain that ''[[Ambystoma velasci]]'' specimens were not included in the original shipment.{{Citation needed|date=October 2021}} Vilem Laufberger in Prague used thyroid hormone injections to induce an axolotl to grow into a terrestrial adult salamander. The experiment was repeated by Englishman [[Julian Huxley]], who was unaware the experiment had already been done, using ground thyroids.<ref name=":4">{{Cite journal|last1=Reiß|first1=Christian|last2=Olsson|first2=Lennart|last3=Hoßfeld|first3=Uwe|date=2015|title=The history of the oldest self-sustaining laboratory animal: 150 years of axolotl research|url=https://onlinelibrary.wiley.com/doi/abs/10.1002/jez.b.22617|journal=Journal of Experimental Zoology Part B: Molecular and Developmental Evolution|language=en|volume=324|issue=5|pages=393–404|doi=10.1002/jez.b.22617|pmid=25920413|bibcode=2015JEZB..324..393R |issn=1552-5015}}</ref> Since then, experiments have been done often with injections of iodine or various thyroid hormones used to induce metamorphosis.<ref name=":5">{{Cite journal|last1=Safi|first1=Rachid|last2=Bertrand|first2=Stéphanie|last3=Marchand|first3=Oriane|last4=Duffraisse|first4=Marilyne|last5=de Luze|first5=Amaury|last6=Vanacker|first6=Jean-Marc|last7=Maraninchi|first7=Marie|last8=Margotat|first8=Alain|last9=Demeneix|first9=Barbara|last10=Laudet|first10=Vincent|date=2004-02-01|title=The Axolotl (''Ambystoma mexicanum''), a Neotenic Amphibian, Expresses Functional Thyroid Hormone Receptors|journal=Endocrinology|volume=145|issue=2|pages=760–772|doi=10.1210/en.2003-0913|pmid=14576183 |doi-access=free}}</ref>