Editing Cyclin-dependent kinase complex (section)

====G<sub>2</sub> to M phase progression====
At the end of S phase, cyclin A is associated with Cdk1 and Cdk2.  During G2 phase, cyclin A is degraded, while cyclin B is synthesized and cyclin B-Cdk1 complexes form.  Not only are cyclin B-Cdk1 complexes important for the transition into M phase, but these CDKCs play a role in the following regulatory and structural processes:<ref name=Malumbres /> 
* Chromosomal condensation
* Fragmentation of Golgi network
* Breakdown of nuclear lamina

Inactivation of the cyclin B-Cdk1 complex through the degradation of cyclin B is necessary for exit out of the M phase of the cell cycle.<ref name=Malumbres />