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Essential tremor
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==== Alcohol ==== Alcohol had been known to help provide short-term relief of tremor symptoms in some people, however, the therapeutic effects of alcohol on ET had not been studied in many clinical trials. It has been proposed that alcohol can help reduce tremors through the agonism mechanism of the gamma-aminobutyric acid GABAergic.<ref>{{cite journal | vauthors = Ondo WG | title = Current and Emerging Treatments of Essential Tremor | journal = Neurologic Clinics | volume = 38 | issue = 2 | pages = 309β323 | date = May 2020 | pmid = 32279712 | doi = 10.1016/j.ncl.2020.01.002 }}</ref> Since GABA can decrease neural activity, it is believed that alcohol can increase the activity of GABA which then can reduce involuntary muscle movements or tremors. However, the duration of action of alcohol on ET is around 3β4 hours, alcohol also had been associated with the rebound of tremor, not to mention the risk of development of long-term alcohol consumption and abuse.<ref name=":0" /> The use of alcohol as a possible treatment for ET is not recommended by healthcare providers.
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