Editing Functional genomics (section)

====RNA sequencing====
{{Main|RNA-Seq|MicroRNA sequencing}}
RNA sequencing has taken over microarray and SAGE technology in recent years, as noted in 2016, and has become the most efficient way to study  transcription and gene expression. This is typically done by [[DNA sequencing|next-generation sequencing]].<ref>{{cite journal | vauthors = Hrdlickova R, Toloue M, Tian B | title = RNA-Seq methods for transcriptome analysis | journal = Wiley Interdisciplinary Reviews: RNA | volume = 8 | issue = 1 | pages = e1364 | date = January 2017 | pmid = 27198714 | pmc = 5717752 | doi = 10.1002/wrna.1364 }}</ref>

A subset of sequenced RNAs are small RNAs, a class of non-coding RNA molecules that are key regulators of transcriptional and post-transcriptional gene silencing, or [[RNA silencing]]. Next-generation sequencing is the gold standard tool for [[non-coding RNA]] discovery, profiling and expression analysis.