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Hyperthyroidism
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===Beta-blockers=== Many of the common symptoms of hyperthyroidism such as palpitations, trembling, and anxiety are mediated by increases in beta-adrenergic receptors on cell surfaces. [[Beta blockers]], typically used to treat high blood pressure, are a class of drugs that offset this effect, reducing rapid pulse associated with the sensation of palpitations, and decreasing tremor and anxiety. Thus, a person with hyperthyroidism can often obtain immediate temporary relief until the hyperthyroidism can be characterized with the Radioiodine test noted above and more permanent treatment take place. Note that these drugs do not treat hyperthyroidism or any of its long-term effects if left untreated, but, rather, they treat or reduce only symptoms of the condition.<ref>{{Cite web|title=UpToDate|url=https://www.uptodate.com/contents/beta-blockers-in-the-treatment-of-hyperthyroidism|access-date=2021-05-17|website=www.uptodate.com}}</ref> Some minimal effect on thyroid hormone production however also comes with [[propranolol]]—which has two roles in the treatment of hyperthyroidism, determined by the different isomers of propranolol. L-propranolol causes beta-blockade, thus treating the symptoms associated with hyperthyroidism such as tremor, palpitations, anxiety, and [[heat intolerance]]. D-propranolol inhibits thyroxine deiodinase, thereby blocking the conversion of T<sub>4</sub> to T<sub>3</sub>, providing some though minimal therapeutic effect. Other beta-blockers are used to treat only the symptoms associated with hyperthyroidism.<ref>{{cite journal | vauthors = Eber O, Buchinger W, Lindner W, Lind P, Rath M, Klima G, Langsteger W, Költringer P | title = The effect of D- versus L-propranolol in the treatment of hyperthyroidism | journal = Clinical Endocrinology | volume = 32 | issue = 3 | pages = 363–372 | date = March 1990 | pmid = 2344697 | doi = 10.1111/j.1365-2265.1990.tb00877.x | s2cid = 37948268 }}</ref> [[Propranolol]] in the UK, and [[metoprolol]] in the US, are most frequently used to augment treatment for people with hyperthyroid .<ref name=pmid1352658>{{cite journal | vauthors = Geffner DL, Hershman JM | title = Beta-adrenergic blockade for the treatment of hyperthyroidism | journal = The American Journal of Medicine | volume = 93 | issue = 1 | pages = 61–68 | date = July 1992 | pmid = 1352658 | doi = 10.1016/0002-9343(92)90681-Z }}</ref>
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