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Infective endocarditis
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===Fungal=== Fungal endocarditis (FE) is often fatal and one of the most serious forms of infective endocarditis. The types of fungi most seen associated with this disease are: ''[[Candida albicans]]'' is found as a spherical or oval budding [[yeast]]. It is associated with endocarditis in people who inject drugs, patients with [[Artificial heart valve|prosthetic valves]], and [[immunocompromised]] patients. It forms biofilms around thick-walled resting structures like prosthetic heart valves and additionally colonizes and penetrates [[Endothelium|endothelial]] walls.<ref name="Bagg_2006" /> C. albicans is responsible for 24-46% of all the cases of FE, and its [[mortality rate]] is 46.6β50%.<ref name=":1">{{cite journal | vauthors = Yuan SM | title = Fungal Endocarditis | journal = Brazilian Journal of Cardiovascular Surgery | volume = 31 | issue = 3 | pages = 252β255 | date = 2016 | pmid = 27737409 | pmc = 5062704 | doi = 10.5935/1678-9741.20160026 | doi-broken-date = 1 November 2024 }}</ref> Other fungi demonstrated to cause endocarditis are ''[[Histoplasma capsulatum]]'' and [[Aspergillus]].<ref name="Lamas" /> Aspergillus contributes to roughly 25% of FE cases.<ref name=":1" /> Endocarditis with ''Tricosporon asahii'' has also been reported in a case report.<ref>{{cite journal | vauthors = Izumi K, Hisata Y, Hazama S | title = A rare case of infective endocarditis complicated by Trichosporon asahii fungemia treated by surgery | journal = Annals of Thoracic and Cardiovascular Surgery | volume = 15 | issue = 5 | pages = 350β3 | date = October 2009 | pmid = 19901894 }}</ref>
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