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Interferon beta-1a
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====Cinnovex==== Cinnovex is the brand name of recombinant Interferon beta-1a, which is manufactured as biosimilar/biogeneric in [[Iran]]. It is produced in a lyophilized form and sold with [[distilled water]] for injection. Cinnovex was developed at the [[Fraunhofer Society]] in collaboration with [[CinnaGen]], and is the first therapeutic protein from a [[Fraunhofer Society|Fraunhofer laboratory]] to be approved as biogeneric / biosimilar medicine. There are several clinical studies to prove the similarity of CinnoVex and Avonex.<ref>{{cite journal | vauthors = Nafissi S, Azimi A, Amini-Harandi A, Salami S, shahkarami MA, Heshmat R | title = Comparing efficacy and side effects of a weekly intramuscular biogeneric/biosimilar interferon beta-1a with Avonex in relapsing remitting multiple sclerosis: a double blind randomized clinical trial | journal = Clinical Neurology and Neurosurgery | volume = 114 | issue = 7 | pages = 986β989 | date = September 2012 | pmid = 22429566 | doi = 10.1016/j.clineuro.2012.02.039 | s2cid = 9236986 }}</ref> A more water-soluble variant is currently being investigated by the Vakzine Projekt Management (VPM) GmbH in Braunschweig, Germany.
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