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Inverted repeat
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===Common in different organisms=== Past studies suggest that repeats are a common feature of [[eukaryotes]] unlike the [[prokaryotes]] and [[archaea]].<ref name=Heringa>{{cite journal|last=Heringa|first=J|title=Detection of internal repeats: how common are they?|journal=Current Opinion in Structural Biology|date=June 1998|volume=8|issue=3|pages=338β45|pmid=9666330|doi=10.1016/S0959-440X(98)80068-7}}</ref> Other reports suggest that irrespective of the comparative shortage of repeat elements in prokaryotic genomes, they nevertheless contain hundreds or even thousands of large repeats.<ref>{{cite journal|last=Treangen|first=TJ|author2=Abraham, AL |author3=Touchon, M |author4= Rocha, EP |title=Genesis, effects and fates of repeats in prokaryotic genomes|journal=FEMS Microbiology Reviews|date=May 2009|volume=33|issue=3|pages=539β71|pmid=19396957|doi=10.1111/j.1574-6976.2009.00169.x|url=https://academic.oup.com/femsre/article-pdf/33/3/539/18141891/33-3-539.pdf|doi-access=free}}</ref> Current genomic analysis seem to suggest the existence of a large excess of perfect inverted repeats in many prokaryotic genomes as compared to eukaryotic genomes.<ref name=Ladoukakis>{{cite journal|last=Ladoukakis|first=ED|author2=Eyre-Walker, A|title=The excess of small inverted repeats in prokaryotes|journal=Journal of Molecular Evolution|date=September 2008|volume=67|issue=3|pages=291β300|pmid=18696026|doi=10.1007/s00239-008-9151-z|url=http://www.lifesci.susx.ac.uk/home/Adam_Eyre-Walker/Website/Publications_files/LadoukakisJME08.pdf|bibcode=2008JMolE..67..291L|citeseerx=10.1.1.578.7466|s2cid=29953202}}</ref> [[File:Pseudoknot-Inverted-Repeats.gif|thumb|500 px| Pseudoknot with four sets of inverted repeats. Inverted repeats 1 and 2 create the stem for stem-loop A and are part of the loop for stem-loop B. Similarly, inverted repeats 3 and 4 form the stem for stem-loop B and are part of the loop for stem-loop A.]] For quantification and comparison of inverted repeats between several species, namely on archaea, see <ref>{{cite book|last=Hosseini|first=M|author2=Pratas, D |author3=Pinho, AJ |title= 11th International Conference on Practical Applications of Computational Biology & Bioinformatics|chapter=On the Role of Inverted Repeats in DNA Sequence Similarity|series=Advances in Intelligent Systems and Computing|publisher=Springer|volume=616|pages=228β236|date=2017|doi=10.1007/978-3-319-60816-7_28|isbn=978-3-319-60815-0}}</ref>
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