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Mesentery
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=== Surgery === While the total mesorectal excision (TME) operation has become the surgical gold standard for the management of rectal cancer, this is not so for colon cancer.<ref name="Coffey"/><ref name="Sehgal">{{cite journal|last1=Sehgal|first1=R|last2=Coffey|first2=JC|title=The development of consensus for complete mesocolic excision (CME) should commence with standardisation of anatomy and related terminology.|journal=International Journal of Colorectal Disease|date=June 2014|volume=29|issue=6|pages=763β4|doi=10.1007/s00384-014-1852-8|pmid=24676507|s2cid=10393183}}</ref> Recently, the surgical principles underpinning TME in rectal cancer have been extrapolated to colonic surgery.<ref>{{cite journal |vauthors=West NP, Morris EJ, Rotimi O, Cairns A, Finan PJ, Quirke P |title=Pathology grading of colon cancer surgical resection and its association with survival: a retrospective observational study |journal=The Lancet Oncology |volume=9 |issue=9 |pages=857β65 |date=September 2008 |pmid=18667357 |doi=10.1016/S1470-2045(08)70181-5}}</ref><ref>{{cite journal |vauthors=SΓΈndenaa K, Quirke P, Hohenberger W, etal |title=The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery : proceedings of a consensus conference |journal=International Journal of Colorectal Disease |volume=29 |issue=4 |pages=419β28 |date=April 2014 |pmid=24477788 |doi=10.1007/s00384-013-1818-2|s2cid=6464670 }}</ref> Total or complete mesocolic excision (CME), use planar surgery and extensive mesenterectomy (high tie) to minimise breach of the mesentery and maximise lymph nodes yield. Application of this T/CME reduces local five-year recurrence rates in colon cancer from 6.5% to 3.6%, while cancer-related five-year survival rates in patients resected for cure increased from 82.1% to 89.1%.<ref name=":11">{{cite journal |vauthors=Hohenberger W, Weber K, Matzel K, Papadopoulos T, Merkel S |title=Standardized surgery for colonic cancer: complete mesocolic excision and central ligation β technical notes and outcome |journal=Colorectal Disease |volume=11 |issue=4 |pages=354β64; discussion 364β5 |date=May 2009 |pmid=19016817 |doi=10.1111/j.1463-1318.2008.01735.x|s2cid=24215331 }}</ref>
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