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Missense mutation
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=== Future Technology and Research === [[Gene therapy]] is being explored as a treatment for missense mutations. This involves inserting the correct sequence of DNA into an incorrect gene.<ref name=":12" /> Artificial Intelligence programs, such as AlphaFold, are also being developed to predict the effect of missense mutations.<ref name=":17" /> Identifying potential deleterious mutations can assist with disease diagnosis and treatment.<ref name=":17">{{Cite journal |last=Cheng |first=Jun |last2=Novati |first2=Guido |last3=Pan |first3=Joshua |last4=Bycroft |first4=Clare |last5=Žemgulytė |first5=Akvilė |last6=Applebaum |first6=Taylor |last7=Pritzel |first7=Alexander |last8=Wong |first8=Lai Hong |last9=Zielinski |first9=Michal |last10=Sargeant |first10=Tobias |last11=Schneider |first11=Rosalia G. |last12=Senior |first12=Andrew W. |last13=Jumper |first13=John |last14=Hassabis |first14=Demis |last15=Kohli |first15=Pushmeet |date=2023-09-22 |title=Accurate proteome-wide missense variant effect prediction with AlphaMissense |url=https://www.science.org/doi/10.1126/science.adg7492 |journal=Science |language=en |volume=381 |issue=6664 |doi=10.1126/science.adg7492 |issn=0036-8075|url-access=subscription }}</ref>
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