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Nebulizer
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===Electrical=== ====Ultrasonic wave nebulizer==== Ultrasonic wave nebulizers were invented in 1965<ref>{{cite patent|url = http://pdfpiw.uspto.gov/.piw?PageNum=0&docid=03243122|country = US|title = Ultrasonic Spray Apparatus|inventor = Snaper, Alvin A.|number = 3243122|status = patent|pubdate = 29 March 1966|fdate = 24 February 1965}} {{Webarchive|url=https://web.archive.org/web/20181029191628/http://pdfpiw.uspto.gov/.piw?PageNum=0&docid=03243122 |date=29 October 2018 }}</ref> as a new type of portable nebulizer. The technology inside an ultrasonic wave nebulizer is to have an [[electronic oscillator]] generate a high frequency [[ultrasonic wave]], which causes the mechanical vibration of a [[piezoelectric]] element. This vibrating element is in contact with a liquid reservoir and its high frequency vibration is sufficient to produce a vapor mist<ref name="Ultrasonic humidifier">{{cite web|url=http://www.airwin-luftbefeuchter.de/html/en/operating_principle.html|author=BOGA Gmbh|title=Operating principle of ultrasonic humidifier|access-date=2010-04-05|url-status=dead|archive-url=https://web.archive.org/web/20101114085152/http://www.airwin-luftbefeuchter.de/html/en/operating_principle.html|archive-date=2010-11-14}}</ref> via [[ultrasonic atomization]]. As they create aerosols from ultrasonic vibration instead of using a heavy air compressor, they only have a weight around {{convert|170|g}}. Another advantage is that the ultrasonic vibration is almost silent. Examples of these more modern type of nebulizers are: [[Omron]] NE-U17 and Beurer Nebulizer IH30.<ref>{{cite book |author1=Knoch, M. |author2=Finlay, W.H. |chapter=Ch. 71 Nebuliser Technologies |editor1=Rathbone |editor2=Hadgraft |editor3=Roberts |title=Modified-Release Drug Delivery Technology |publisher=Marcel Dekker |year=2002 |pages=849β856 }}</ref> ====Vibrating mesh technology==== A new significant innovation was made in the nebulizer market around 2005, with creation of the ultrasonic Vibrating Mesh Technology (VMT). With this technology a mesh/membrane with 1000β7000 laser drilled holes vibrates at the top of the liquid reservoir, and thereby pressures out a mist of very fine droplets through the holes. This technology is more efficient than having a vibrating piezoelectric element at the bottom of the liquid reservoir, and thereby shorter treatment times are also achieved. The old problems found with the ultrasonic wave nebulizer, having too much liquid waste and undesired heating of the medical liquid, have also been solved by the new vibrating mesh nebulizers. Available VMT nebulizers include: Pari eFlow,<ref name="VMT1">{{cite web|url=http://www.paripharma.com/technologies1.htm|author=PARI Pharma|title=Leading aerosol therapies worldwide, delivery with eFlow|year=2008|access-date=2010-04-09|url-status=dead|archive-url=https://web.archive.org/web/20100328172026/http://www.paripharma.com/technologies1.htm|archive-date=2010-03-28}}</ref> [[Respironics]] i-Neb,<ref name="VMT2">{{cite web|url=http://ineb.respironics.com/AADHow.asp|author=Philips Respironics|title=Active Aerosol Delivery, The I-neb and Vibrating Mesh Technology|year=2010|access-date=2010-04-09|url-status=dead|archive-url=https://web.archive.org/web/20100804054557/http://ineb.respironics.com/AADHow.asp|archive-date=2010-08-04}}</ref> Beurer Nebulizer IH50,<ref name="VMT4">{{cite web|url=http://www.beurer.com/web/en/products/nebulization/nebulization/IH-50|author=Beurer|title=Product details of IH50 nebulizer, with a vibrating membrane|year=2015|access-date=2015-04-21|archive-date=2015-05-13|archive-url=https://web.archive.org/web/20150513010354/http://www.beurer.com/web/en/products/nebulization/nebulization/IH-50|url-status=dead}}</ref> and Aerogen Aeroneb.<ref name="VMT5">{{cite web|url=http://aerogen.com/technology.html|author=Aerogen|title=Micropump nebulizers, Aeroneb, Vibrating Mesh Technology|year=2009|access-date=2010-04-09|url-status=dead|archive-url=https://web.archive.org/web/20100203152617/http://aerogen.com/technology.html|archive-date=2010-02-03}}</ref> As the price of the ultrasonic VMT nebulizers is higher than models using previous technologies, most manufacturers continue to also sell the classic jet nebulizers.<ref>{{Cite web|title=Nebulizer Machine and Its Overview|url=http://www.indexofsciences.com/nebulizer-machine-and-its-overview/|last=Team|first=Editorial|date=2019-12-09|website=Index of Sciences|language=en-US|access-date=2020-05-25}}</ref>
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