Editing Plasmodium falciparum (section)

=====Trophozoite=====
After invading the erythrocyte, the parasite loses its specific invasion organelles (apical complex and surface coat) and de-differentiates into a round trophozoite located within a parasitophorous vacuole. The trophozoite feeds on the haemoglobin of the erythrocyte, digesting its proteins and converting (by [[biocrystallization]]) the remaining heme into insoluble and chemically inert β-hematin [[crystals]] called haemozoin.<ref>{{cite journal |last1=Pagola |first1=Silvina |last2=Stephens |first2=Peter W. |last3=Bohle |first3=D. Scott |last4=Kosar |first4=Andrew D. |last5=Madsen |first5=Sara K. |title=The structure of malaria pigment β-haematin |journal=Nature |date=March 2000 |volume=404 |issue=6775 |pages=307–310 |doi=10.1038/35005132 |bibcode=2000Natur.404..307P|pmid=10749217|s2cid=4420567}}</ref><ref>{{cite journal |last1=Hempelmann |first1=Ernst |title=Hemozoin Biocrystallization in ''Plasmodium falciparum'' and the antimalarial activity of crystallization inhibitors |journal=Parasitology Research |date=1 March 2007 |volume=100 |issue=4 |pages=671–676 |doi=10.1007/s00436-006-0313-x |language=en |issn=1432-1955 |s2cid=30446678 |pmid=17111179}}</ref> The young trophozoite (or "ring" stage, because of its morphology on stained blood films) grows substantially before undergoing multiplication.<ref name="1.5">{{cite web | title = Malaria eModule – ASEXUAL ERYTHROCYTIC STAGES | url = http://www.impact-malaria.com/FR/EPS/Formations_et_cours_internationaux/Formation_de_la_Liverpool_School_LSTMH/cours_liverpool/Unit_1/1_5.html | access-date = 2017-06-04 | archive-date = 2007-12-22 | archive-url = https://web.archive.org/web/20071222163324/http://www.impact-malaria.com/FR/EPS/Formations_et_cours_internationaux/Formation_de_la_Liverpool_School_LSTMH/cours_liverpool/Unit_1/1_5.html | url-status = dead }}</ref>