Editing Preterm birth (section)

===Placental alpha microglobulin-1===
[[Placental alpha microglobulin-1 (PAMG-1)]] has been the subject of several investigations evaluating its ability to predict imminent spontaneous preterm birth in women with signs, symptoms, or complaints suggestive of [[preterm labor]].<ref name="pmid17329514">{{cite journal | vauthors = Lee SE, Park JS, Norwitz ER, Kim KW, Park HS, Jun JK | title = Measurement of placental alpha-microglobulin-1 in cervicovaginal discharge to diagnose rupture of membranes | journal = Obstetrics and Gynecology | volume = 109 | issue = 3 | pages = 634–640 | date = March 2007 | pmid = 17329514 | doi = 10.1097/01.AOG.0000252706.46734.0a | s2cid = 20732037 }}</ref><ref>{{cite journal | vauthors = Lee SM, Lee J, Seong HS, Lee SE, Park JS, Romero R, Yoon BH | title = The clinical significance of a positive Amnisure test in women with term labor with intact membranes | journal = The Journal of Maternal-Fetal & Neonatal Medicine | volume = 22 | issue = 4 | pages = 305–310 | date = April 2009 | pmid = 19350444 | pmc = 2744034 | doi = 10.1080/14767050902801694 }}</ref><ref>{{cite journal |vauthors=Lee SM, Yoon BH, Park CW, Kim SM, Park JW | year = 2011 | title = Intra-amniotic inflammation in patients with a positive Amnisure test in preterm labor and intact membranes | journal = Am J Obstet Gynecol | volume = 204 | issue = 1| page = S209 | doi=10.1016/j.ajog.2010.10.543}}</ref><ref>{{cite journal | vauthors = Lee SM, Romero R, Park JW, Kim SM, Park CW, Korzeniewski SJ, Chaiworapongsa T, Yoon BH | display-authors = 6 | title = The clinical significance of a positive Amnisure test in women with preterm labor and intact membranes | journal = The Journal of Maternal-Fetal & Neonatal Medicine | volume = 25 | issue = 9 | pages = 1690–1698 | date = September 2012 | pmid = 22280400 | pmc = 3422421 | doi = 10.3109/14767058.2012.657279 }}</ref><ref>{{cite journal | vauthors = Sukchaya K, Phupong V | title = A comparative study of positive rate of placental α-microglobulin-1 test in pre-term pregnant women with and without uterine contraction | journal = Journal of Obstetrics and Gynaecology | volume = 33 | issue = 6 | pages = 566–568 | date = August 2013 | pmid = 23919851 | doi = 10.3109/01443615.2013.807786 | s2cid = 20265539 }}</ref><ref>{{cite journal | vauthors = Nikolova T, Bayev O, Nikolova N, Di Renzo GC | title = Evaluation of a novel placental alpha microglobulin-1 (PAMG-1) test to predict spontaneous preterm delivery | journal = Journal of Perinatal Medicine | volume = 42 | issue = 4 | pages = 473–477 | date = July 2014 | pmid = 24334429 | doi = 10.1515/jpm-2013-0234 | s2cid = 6547430 }}</ref> In one investigation comparing this test to [[fetal fibronectin]] testing and cervical length measurement via [[transvaginal ultrasound]], the test for PAMG-1 (commercially known as the PartoSure test) has been reported to be the single best predictor of imminent spontaneous delivery within 7 days of a patient presenting with signs, symptoms, or complaints of preterm labor. Specifically, the PPV, or [[positive predictive value]], of the tests were 76%, 29%, and 30% for PAMG-1, fFN and CL, respectively (P < 0.01).<ref>Nikolova T, Bayev O, Nikolova N, Di Renzo GC. Comparison of a novel test for placental alpha microglobulin-1 with fetal fibronectin and cervical length measurement for the prediction of imminent spontaneous preterm delivery in patients with threatened preterm labor. J Perinat Med. 2015 Jan 6.</ref>