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Prophase
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==== Zygotene ==== In the second phase of prophase I, zygotene (from the Greek for "conjugation"), all maternally and paternally derived [[chromosome]]s have found their [[Homologous chromosome|homologous]] partner.<ref name=":2" />{{rp|98}} The homologous pairs then undergo synapsis,a process by which the [[synaptonemal complex]] (a proteinaceous structure) aligns corresponding regions of [[Nucleic acid sequence|genetic information]] on maternally and paternally derived non-sister [[chromatid]]s of [[homologous chromosome]] pairs.<ref name=":2" />{{rp|98}}<ref name=":3" /> The paired homologous chromosome bound by the [[synaptonemal complex]] are referred to as [[Bivalent (genetics)|bivalents]] or tetrads.<ref name=":1" /><ref name=":2" />{{rp|98}} [[Allosome|Sex (X and Y) chromosomes]] do not fully synapse because only a small region of the chromosomes are homologous.<ref name=":2" />{{rp|98}} The [[nucleolus]] moves from a central to a peripheral position in the [[Cell nucleus|nucleus]].<ref>{{cite journal | vauthors = Zickler D, Kleckner N | title = The leptotene-zygotene transition of meiosis | journal = Annual Review of Genetics | volume = 32 | pages = 619β97 | date = 1998 | pmid = 9928494 | doi = 10.1146/annurev.genet.32.1.619 }}</ref>
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