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Sciatica
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===Other=== Pain that does not improve when lying down suggests a nonmechanical cause, such as [[cancer]], [[inflammation]], or [[infection]].<ref name=tarulli_radiculopathy/> Sciatica can be caused by [[tumors]] impinging on the spinal cord or the nerve roots.<ref name=Valat2010/> Severe back pain extending to the hips and feet, loss of bladder or bowel control, or muscle weakness may result from [[spinal tumor]]s or [[cauda equina syndrome]].<ref name=":2" /> Trauma to the spine, such as from a car accident or hard fall onto the heel or buttocks, may also lead to sciatica.<ref name=":2" /> A relationship has been proposed with a latent ''[[Cutibacterium acnes]]'' infection in the intervertebral discs, but the role it plays is not yet clear.<ref name=GankoRao2015>{{cite journal | vauthors = Ganko R, Rao PJ, Phan K, Mobbs RJ | title = Can bacterial infection by low virulent organisms be a plausible cause for symptomatic disc degeneration? A systematic review | journal = Spine | volume = 40 | issue = 10 | pages = E587β92 | date = May 2015 | pmid = 25955094 | doi = 10.1097/BRS.0000000000000832 | s2cid = 23436352 }}</ref><ref name=ChenZhou2016>{{cite journal| vauthors=Chen Z, Cao P, Zhou Z, Yuan Y, Jiao Y, Zheng Y| title=Overview: the role of Propionibacterium acnes in nonpyogenic intervertebral discs. | journal=Int Orthop | year= 2016 | volume= 40 | issue= 6 | pages= 1291β8 | pmid=26820744 | doi=10.1007/s00264-016-3115-5 | s2cid=889041 | type=Review }}</ref>
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