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Silent mutation
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== Further reading == {{refbegin}} * {{cite journal | vauthors = Mueller S, Coleman JR, Wimmer E | title = Putting synthesis into biology: a viral view of genetic engineering through de novo gene and genome synthesis | journal = Chemistry & Biology | volume = 16 | issue = 3 | pages = 337β47 | date = March 2009 | pmid = 19318214 | pmc = 2728443 | doi = 10.1016/j.chembiol.2009.03.002 | quote = By large-scale computer-aided redesign of the viral genome we engineered hundreds of silent mutations into poliovirus. ... We termed this process of perturbing intrinsic viral genome biases by synthetic genome re-design SAVE for ''S''ynthetic ''A''ttenuated ''V''irus ''E''ngineering }} {{refend}}
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