Editing Cyclin-dependent kinase complex (section)

==Other==
Even though the majority of the known CDKCs are involved in the cell cycle, not all kinase complexes function in this manner.  Studies have shown other CDKCs, such as cyclin k-Cdk9 and cyclin T1-Cdk9, are involved in the [[replication stress]] response,<ref>Yu DS, Zhao R, Hsu EL, Cayer J, Ye F, Guo Y, Shyr Y, Cortez D.  Cyclin-dependent kinase 9-cyclin K functions in the replication stress response.  EMBO Rep. 2010 Nov;11(11):876-82.</ref> and influence [[transcription (biology)|transcription]].<ref>Fu TJ, Peng J, Lee G, Price DH, Flores O.  Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription. J Biol Chem. 1999 Dec 3;274(49):34527-30.</ref><ref>Yang Z, Zhu Q, Luo K, Zhou Q.  The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription. Nature. 2001 Nov 15;414(6861):317-22.</ref><ref>Yu DS, Cortez D.  A role for CDK9-cyclin K in maintaining genome integrity.  Cell Cycle. 2011 Jan 1;10(1):28-32.</ref> Additionally, cyclin H-Cdk7 complexes may play a role in [[meiosis]] in male germ cells,<ref>Kim JM, McGaughy JT, Bogle RK, Ravnik SE.  Meiotic expression of the cyclin H/Cdk7 complex in male germ cells of the mouse.  Biol Reprod. 2001 May;64(5):1400-8.</ref> and has been shown to be involved in transcriptional activities as well.<ref name=Malumbres /><ref>Patel SA, Simon MC.  Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryos.  J Biol Chem. 2010 May 14;285(20):15587-98.</ref>