Editing Deep brain stimulation (section)

====Genitourinary and other symptoms====
Benefit after STN DBS has been reported in nonmotor fluctuating symptoms, including urinary dysfunction, [[sialorrhea]], sleep, PD-related pain, and off-period sweating.<ref name = "JAMA Neurol 2018"/>
[[File:Globus pallidus small.gif|thumb|260px|The globus pallidus is targeted in both Parkinson's and dystonia.]]

A meta analysis predominantly looking at DBS to the STN found it led to less urinary urgency, increased bladder capacity and maximum urinary flow rate.<ref>{{cite journal |last1=Gao |first1=L |last2=Wang |first2=M |last3=Zhou |first3=M |last4=Yin |first4=W |last5=Cao |first5=X |title=Impact of deep brain stimulation on urogenital function in Parkinson's disease: a systematic review and meta-analysis. |journal=Frontiers in Neurology |date=2024 |volume=15 |page=1397344 |doi=10.3389/fneur.2024.1397344 |doi-access=free |pmid=39026583|pmc=11254620 }}</ref> Another meta analysis study further distinguished effects by target subgroups, finding that DBS of the GPi and STN have an inhibitory effect on [[detrusor muscle|detrusor]] function at the [[pelvic floor]], leading to an increase in functional urine capacity and retention. DBS of the VIM has the opposite effect, leading to detrusor excitation and improved voiding.<ref>{{cite journal |last1=Jörg |first1=E |last2=Sartori |first2=AM |last3=Hofer |first3=AS |last4=Baumann |first4=CR |last5=Kessler |first5=TM |title=Deep brain stimulation effects on lower urinary tract function: Systematic review and meta-analysis. |journal=Parkinsonism & Related Disorders |date=October 2020 |volume=79 |pages=65–72 |doi=10.1016/j.parkreldis.2020.08.032 |pmid=32889502|doi-access=free }}</ref>