Editing Gallbladder (section)

===Cancer===
{{main|Gallbladder carcinoma}}
Cancer of the gallbladder is uncommon and mostly occurs in later life. When cancer occurs, it is mostly of the glands lining the surface of the gallbladder ([[adenocarcinoma]]).<ref name=DAVIDSONS2010 /> Gallstones are thought to be linked to the formation of cancer. Other risk factors include large (>1&nbsp;cm) [[gallbladder polyp]]s and having a highly calcified [[porcelain gallbladder|"porcelain" gallbladder]].<ref name=DAVIDSONS2010 />

Cancer of the gallbladder can cause attacks of biliary pain, yellowing of the skin ([[jaundice]]), and weight loss. A large gallbladder may be able to be felt in the abdomen. [[Liver function test]]s may be elevated, particularly involving [[Gamma-glutamyltransferase|GGT]] and [[Alkaline phosphatase|ALP]], with ultrasound and CT scans being considered [[medical imaging]] investigations of choice.<ref name=DAVIDSONS2010 /> Cancer of the gallbladder is managed by removing the gallbladder, however, {{as of|2010|alt=as of 2010|post=,}} the prognosis remains poor.<ref name=DAVIDSONS2010 />

Cancer of the gallbladder may also be found incidentally after surgical removal of the gallbladder, with 1–3% of cancers identified in this way. [[Gallbladder polyp]]s are mostly benign growths or lesions resembling growths that form in the gallbladder wall,<ref>{{cite web|title=Gallbladder Polyps|url=http://www.mayoclinic.com/health/gallbladder-polyps/AN01044|website=MayoClinic|access-date=March 19, 2015}}</ref> and are only associated with cancer when they are larger in size (>1&nbsp;cm).<ref name=DAVIDSONS2010 /> Cholesterol polyps, often associated with [[Cholesterolosis of the gallbladder|cholesterolosis]] ("strawberry gallbladder", a change in the gallbladder wall due to excess [[cholesterol]]<ref>[http://cancerweb.ncl.ac.uk/cgi-bin/omd?strawberry+gallbladder Strawberry gallbladder] – cancerweb.ncl.ac.uk.</ref>), often cause no symptoms and are thus often detected in this way.<ref name=DAVIDSONS2010 />