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Inhalant
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===Solvents=== {{Gallery |title=Solvents |width=160 | height=170 |align=center |footer=Example 1 |File:USMC-07664.jpg |A range of petroleum-based products that can be used as inhalants. |File:Sanford king size.jpg |[[Permanent marker]]s have the potential to be inhalants |File:Nail polish drop.jpg |Common household products such as nail polish contain solvents that can be concentrated and inhaled, in a manner not intended by the manufacturer, to produce intoxication. Misuse of products in this fashion can be harmful or fatal. }} A wide range of volatile [[solvents]] intended for household or industrial use are inhaled as [[recreational drugs]]. This includes [[petroleum product]]s (gasoline and [[kerosene]]), [[toluene]] (used in [[paint thinner]], [[permanent markers]], [[contact cement]] and model glue), and [[acetone]] (used in [[nail polish remover]]). These solvents vaporize at room temperature. [[File:Filmas "Džimlai rūdi rallallā" uzņemšana Ministru kabinetā (8650399785).jpg|thumb|Whiteboard marker on a clapperboard.]] Until the early 1990s, the most common solvents that were used for the ink in [[permanent marker]]s were [[toluene]] and [[xylene]]. These two substances are both harmful<ref>{{Cite web|url=https://wwwn.cdc.gov/TSP/MMG/MMGDetails.aspx?mmgid=157&toxid=29|title=Toluene | Medical Management Guidelines | Toxic Substance Portal | ATSDR|website=wwwn.cdc.gov}}</ref><ref>{{Cite web|url=https://healthfully.com/harmful-effects-of-xylene-4564845.html|title=Healthfully|website=Healthfully}}</ref> and characterized by a very strong smell. Today, the ink is usually made on the basis of alcohols (e.g. [[1-Propanol]], [[1-butanol]], [[diacetone alcohol]] and [[cresol]]s). Organochlorine solvents are particularly hazardous; many of these are now restricted in developed countries due to their environmental impact.<ref>{{Cite journal |last=Jayaraj |first=Ravindran |last2=Megha |first2=Pankajshan |last3=Sreedev |first3=Puthur |date=2016-12-01 |title=Review Article. Organochlorine pesticides, their toxic effects on living organisms and their fate in the environment |url=https://www.sciendo.com/article/10.1515/intox-2016-0012 |journal=Interdisciplinary Toxicology |language=en |volume=9 |issue=3-4 |pages=90–100 |doi=10.1515/intox-2016-0012 |issn=1337-9569 |pmc=5464684 |pmid=28652852}}</ref> ====Legality==== [[File:Contact-cement 000000.jpg|thumb|upright=.75|Contact cement, a fast-drying glue, is widely used as an inhalant, as it typically contains solvents such as [[toluene]] which vaporize at room temperature.]] Even though solvent glue is normally a legal product, there is a 1983 case where a court ruled that supplying glue to children is illegal. ''[[Khaliq v HM Advocate]]'' was a Scottish criminal case decided by the [[High Court of Justiciary]] on appeal, in which it was decided that it was an offense at [[common law]] to supply glue-sniffing materials that were otherwise legal in the knowledge that they would be used recreationally by children. Two shopkeepers in [[Glasgow]] were arrested and charged for supplying children with "glue-sniffing kits" consisting of a quantity of petroleum-based glue in a plastic bag. They argued there was nothing illegal about the items that they had supplied. On appeal, the High Court took the view that, even though glue and plastic bags might be perfectly legal, everyday items, the two shopkeepers knew perfectly well that the children were going to use the articles as inhalants and the charge on the indictment should stand.<ref>SCCR p 492{{full citation needed|date=January 2020}}</ref> When the case came to trial at Glasgow High Court the two were sentenced to three years' imprisonment. As of 2023, in England, Scotland, and Wales it is illegal to sell inhalants, including solvent glues, to persons of any age likely to use them as an intoxicant.<ref name="talktofrank.com"/> As of 2017, thirty-seven US states impose criminal penalties on some combination of sale, possession or recreational use of various inhalants. In 15 of these states, such laws apply only to persons under the age of 18.<ref name="nationaltasc.org"/> ====Gasoline==== Gasoline sniffing can cause [[lead poisoning]],<ref name="pmid7139470">{{cite journal |author=Ross CA |title=Gasoline sniffing and lead encephalopathy |journal=Can Med Assoc J |volume=127 |issue=12 |pages=1195–7 |date=December 1982 |pmid=7139470 |pmc=1874752}}</ref> in locations where [[Banning of leaded petrol|leaded gas is not banned]]. ====Toluene==== [[Toluene]] can damage [[myelin]].<ref name="pmid14748556">{{cite journal |vauthors=Filley CM, Halliday W, Kleinschmidt-DeMasters BK |title=The effects of toluene on the central nervous system |journal=J. Neuropathol. Exp. Neurol. |volume=63 |issue=1 |pages=1–12 |date=January 2004 |pmid=14748556 |doi=10.1093/jnen/63.1.1 |doi-access=free }}</ref>
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