Open main menu
Home
Random
Recent changes
Special pages
Community portal
Preferences
About Wikipedia
Disclaimers
Incubator escapee wiki
Search
User menu
Talk
Dark mode
Contributions
Create account
Log in
Editing
MDMA
(section)
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
===During pregnancy=== MDMA is a moderately [[teratogenic drug]] (i.e., it is toxic to the fetus).<ref name=vorhees>{{cite journal | vauthors = Vorhees CV | title = Methods for detecting long-term CNS dysfunction after prenatal exposure to neurotoxins | journal = Drug and Chemical Toxicology | volume = 20 | issue = 4 | pages = 387β99 | date = November 1997 | pmid = 9433666 | doi = 10.3109/01480549709003895 }}</ref><ref name=meamar>{{cite journal | vauthors = Meamar R, Karamali F, Sadeghi HM, Etebari M, Nasr-Esfahani MH, Baharvand H | title = Toxicity of ecstasy (MDMA) towards embryonic stem cell-derived cardiac and neural cells | journal = Toxicology in Vitro | volume = 24 | issue = 4 | pages = 1133β8 | date = June 2010 | pmid = 20230888 | doi = 10.1016/j.tiv.2010.03.005 | bibcode = 2010ToxVi..24.1133M | quote = In summary, MDMA is a moderate teratogen that could influence cardiac and neuronal differentiation in the ESC model and these results are in concordance with previous in vivo and in vitro models. }}</ref> [[Uterus|In utero]] exposure to MDMA is associated with a [[neurotoxicity|neuro]]- and [[cardiotoxicity]]<ref name=meamar/> and impaired motor functioning. Motor delays may be temporary during infancy or long-term. The severity of these developmental delays increases with heavier MDMA use.<ref name=Pharm2014 /><ref name=singer>{{cite journal | vauthors = Singer LT, Moore DG, Fulton S, Goodwin J, Turner JJ, Min MO, Parrott AC | title = Neurobehavioral outcomes of infants exposed to MDMA (Ecstasy) and other recreational drugs during pregnancy | journal = Neurotoxicology and Teratology | volume = 34 | issue = 3 | pages = 303β10 | year = 2012 | pmid = 22387807 | pmc = 3367027 | doi = 10.1016/j.ntt.2012.02.001 | bibcode = 2012NTxT...34..303S }}</ref> MDMA has been shown to promote the survival of fetal dopaminergic neurons in culture.<ref>{{cite journal | vauthors = Lipton JW, Tolod EG, Thompson VB, Pei L, Paumier KL, Terpstra BT, Lynch KA, Collier TJ, Sortwell CE | title = 3,4-Methylenedioxy-N-methamphetamine (ecstasy) promotes the survival of fetal dopamine neurons in culture | journal = Neuropharmacology | volume = 55 | issue = 5 | pages = 851β859 | date = October 2008 | pmid = 18655796 | doi = 10.1016/j.neuropharm.2008.06.062 | pmc = 2572681 }}</ref>
Edit summary
(Briefly describe your changes)
By publishing changes, you agree to the
Terms of Use
, and you irrevocably agree to release your contribution under the
CC BY-SA 4.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)