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Neurulation
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==Neural tube defects== {{Main|Neural tube defect}} Failure of neurulation, especially failure of closure of the neural tube are among the most common and disabling [[birth defect]]s in humans, occurring in roughly 1 in every 500 live births.<ref>Daley, Darrel. [http://faculty.ncwc.edu/Ddaley/B308.Form.nervous.sys.epid.htm Formation of the Nervous System] {{Webarchive|url=https://web.archive.org/web/20080103131405/http://faculty.ncwc.edu/Ddaley/B308.Form.nervous.sys.epid.htm |date=2008-01-03 }}. Last accessed on Oct 29, 2007.</ref> Failure of the rostral end of the neural tube to close results in [[anencephaly]], or lack of brain development, and is most often fatal.<ref>{{Cite web|url=https://ghr.nlm.nih.gov/condition/anencephaly|title=Anencephaly|last=Reference|first=Genetics Home|website=Genetics Home Reference|language=en|access-date=2020-03-02}}</ref> Failure of the caudal end of the neural tube to close causes a condition known as [[spina bifida]], in which the spinal cord fails to close.<ref>{{Cite web|url=https://www.cdc.gov/ncbddd/spinabifida/facts.html|title=Spina Bifida Facts {{!}} CDC|last=CDC|date=2018-08-31|website=Centers for Disease Control and Prevention|language=en-us|access-date=2020-03-02}}</ref>
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