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Radioactive tracer
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===Technetium=== {{main|technetium-99m}} [[Technetium-99m|<sup>99m</sup>Tc]] is a very versatile radioisotope, and is the most commonly used radioisotope tracer in medicine. It is easy to produce in a [[technetium-99m generator]], by decay of [[molybdenum|<sup>99</sup>Mo]]. :<sup>99</sup>Mo β <sup>99m</sup>Tc + {{Subatomic particle|Electron-}} + {{Subatomic particle|Electron antineutrino}} The molybdenum isotope has a half-life of approximately 66 hours (2.75 days), so the generator has a useful life of about two weeks. Most commercial <sup>99m</sup>Tc generators use [[column chromatography]], in which <sup>99</sup>Mo in the form of molybdate, MoO<sub>4</sub><sup>2β</sup> is adsorbed onto acid alumina (Al<sub>2</sub>O<sub>3</sub>). When the <sup>99</sup>Mo decays it forms [[pertechnetate]] TcO<sub>4</sub><sup>β</sup>, which because of its single charge is less tightly bound to the alumina. Pulling normal saline solution through the column of immobilized <sup>99</sup>Mo elutes the soluble <sup>99m</sup>Tc, resulting in a saline solution containing the <sup>99m</sup>Tc as the dissolved sodium salt of the pertechnetate. The pertechnetate is treated with a [[reducing agent]] such as [[tin|Sn<sup>2+</sup>]] and a [[ligand]]. Different ligands form [[coordination complex]]es which give the technetium enhanced affinity for particular sites in the human body. <sup>99m</sup>Tc decays by gamma emission, with a half-life: 6.01 hours. The short half-life ensures that the body-concentration of the radioisotope falls effectively to zero in a few days.
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