Editing TATA box (section)

=== Interactions ===
In specific cell types or on specific promoters TBP can be replaced by one of several TBP-related factors (TRF1 in [[Drosophila]], TBPL1/TRF2 in [[metazoa]]ns, TBPL2/TRF3 in [[vertebrate]]s), some of which interact with the TATA box similar to [[TATA-binding protein|TBP]].<ref>{{cite journal | vauthors = Akhtar W, Veenstra GJ | title = TBP-related factors: a paradigm of diversity in transcription initiation | journal = Cell & Bioscience | volume = 1 | issue = 1 | pages = 23 | date = 1 January 2011 | pmid = 21711503 | pmc = 3142196 | doi = 10.1186/2045-3701-1-23 | doi-access = free }}</ref> Interaction of TATA boxes with a variety of [[Activator (genetics)|activators]] or [[repressor]]s can influence the [[Transcription (biology)|transcription]] of [[gene]]s in many ways{{Citation needed|date=December 2018}}. [[Enhancer (genetics)|Enhancers]] are long-range regulatory elements that increase promoter activity while [[Silencer (genetics)|silencers]] repress promoter activity.