Editing Transient receptor potential channel (section)

===TRPY===
TRPY, Y for "yeast", is highly localized to the yeast vacuole, which is the functional equivalent of a lysosome in a mammalian cell, and acts as a mechanosensor for vacuolar osmotic pressure. Patch clamp techniques and hyperosmotic stimulation have illustrated that TRPY plays a role in intracellular calcium release.<ref>{{cite journal | vauthors = Dong XP, Wang X, Xu H | title = TRP channels of intracellular membranes | journal = Journal of Neurochemistry | volume = 113 | issue = 2 | pages = 313–28 | date = April 2010 | pmid = 20132470 | pmc = 2905631 | doi = 10.1111/j.1471-4159.2010.06626.x }}</ref> Phylogenetic analysis has shown that TRPY1 does not form a part with the other metazoan TRP groups one and two, and is suggested to have evolved after the divergence of metazoans and fungi.<ref name="Kadowaki_evodyn"/> Others have indicated that TRPY are more closely related to TRPP.<ref>{{cite journal | vauthors = Palovcak E, Delemotte L, Klein ML, Carnevale V | title = Comparative sequence analysis suggests a conserved gating mechanism for TRP channels | journal = The Journal of General Physiology | volume = 146 | issue = 1 | pages = 37–50 | date = July 2015 | pmid = 26078053 | pmc = 4485022 | doi = 10.1085/jgp.201411329 }}</ref>