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Biofouling
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====Other methods==== Regimens to periodically use heat to treat exchanger equipment and pipes have been successfully used to remove mussels from power plant cooling systems using water at 105 °F (40 °C) for 30 minutes.<ref>{{citation|title=Oceans 86 Proceedings|contribution=Development of a Site Specific Biofouling Control Program for the Diablo Canyon Power Plant|first=David C.|last=Sommerville|pages=227–231|doi=10.1109/OCEANS.1986.1160543|date=September 1986|publisher=IEEE Conference Publications|s2cid=110171493}}</ref> The medical industry utilizes a variety of energy methods to address [[bioburden]] issues associated with biofouling. [[Autoclave|Autoclaving]] typically involves heating a medical device to 121 °C (249 °F) for 15–20 minutes. Ultrasonic cleaning, UV light, and chemical wipe-down or immersion can also be used for different types of devices. Medical devices used in operating rooms, ICUs, isolation rooms, biological analysis labs, and other high-contamination-risk areas have negative pressure (constant exhaust) in the rooms, maintain strict cleaning protocols, require equipment with no fans, and often drape equipment in protective plastic.<ref>{{cite book |doi=10.1007/978-3-319-99921-0_35 |chapter=Operation Department: Infection Control |title=Prevention and Control of Infections in Hospitals |year=2019 |last1=Andersen |first1=Bjørg Marit |pages=453–489 |isbn=978-3-319-99920-3 |s2cid=86654083 }}</ref> [[Ultraviolet#Subtypes|UVC]] irradiation is a noncontact, nonchemical solution that can be used across a range of instruments. Radiation in the UVC range prevents biofilm formation by deactivating the [[DNA]] in bacteria, viruses, and other microbes. Preventing biofilm formation prevents larger organisms from attaching themselves to the instrument and eventually rendering it inoperable.<ref>Hari Venugopalan, ''Photonic Frontiers: LEDs - UVC LEDs reduce marine biofouling'', Laser Focus World (July 2016) pp. 28–31 [http://www.laserfocusworld.com/articles/print/volume-52/issue-07/features/photonic-frontiers-leds-uvc-leds-reduce-marine-biofouling.html StackPath]</ref>
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