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Burrows–Wheeler transform
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===BWT for compression of genomic databases=== Cox et al.<ref name="Cox, AJ2012">{{cite journal |vauthors= Cox AJ, Bauer MJ, Jakobi T, Rosone G|title=Large-scale compression of genomic sequence databases with the Burrows–Wheeler transform |journal=Bioinformatics |volume=28 |number=11 |pages=1415–1419 |year=2012 | publisher=Oxford University Press |doi=10.1093/bioinformatics/bts173 |pmid=22556365 |arxiv=1205.0192 }}</ref> presented a genomic compression scheme that uses BWT as the algorithm applied during the first stage of compression of several genomic datasets including the human genomic information. Their work proposed that BWT compression could be enhanced by including a second stage compression mechanism called same-as-previous encoding ("SAP"), which makes use of the fact that suffixes of two or more prefix letters could be equal. With the compression mechanism BWT-SAP, Cox et al. showed that in the genomic database ERA015743, 135.5 GB in size, the compression scheme BWT-SAP compresses the ERA015743 dataset by around 94%, to 8.2 GB.
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