Editing Candida albicans (section)

===Role of ''C. albicans'' in Crohn's disease===
The link between ''C. albicans'' and [[Crohn's disease]] has been investigated in a large cohort. This study demonstrated that members of families with multiple cases of Crohn's disease were more likely to be colonized by ''C. albicans'' than members of control families.<ref>{{cite journal | vauthors = Poulain D, Sendid B, Standaert-Vitse A, Fradin C, Jouault T, Jawhara S, Colombel JF | title = Yeasts: neglected pathogens | journal = Digestive Diseases | volume = 27 | issue = Suppl 1 | pages = 104–110 | date = 2009 | pmid = 20203505 | doi = 10.1159/000268129 | s2cid = 9014160 }}</ref> Experimental studies show that chemically induced colitis promotes ''C. albicans'' colonization. In turn, ''C. albicans'' colonization generates anti-''Saccharomyces cerevisiae'' antibodies (ASCA), increases inflammation, histological scores and pro-inflammatory cytokine expression.<ref>{{cite journal | vauthors = Jawhara S, Poulain D | title = Saccharomyces boulardii decreases inflammation and intestinal colonization by Candida albicans in a mouse model of chemically-induced colitis | journal = Medical Mycology | volume = 45 | issue = 8 | pages = 691–700 | date = December 2007 | pmid = 17885943 | doi = 10.1080/13693780701523013 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Jawhara S, Thuru X, Standaert-Vitse A, Jouault T, Mordon S, Sendid B, Desreumaux P, Poulain D | display-authors = 6 | title = Colonization of mice by Candida albicans is promoted by chemically induced colitis and augments inflammatory responses through galectin-3 | journal = The Journal of Infectious Diseases | volume = 197 | issue = 7 | pages = 972–980 | date = April 2008 | pmid = 18419533 | doi = 10.1086/528990 | doi-access = free }}</ref>