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Comparative genomics
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===Agriculture=== [[Agriculture]] is a field that reaps the benefits of comparative genomics. Identifying the [[Locus (genetics)|loci]] of advantageous genes is a key step in [[crop breeding|breeding crops]] that are optimized for greater [[crop yield|yield]], cost-efficiency, quality, and [[disease resistance]]. For example, one [[genome wide association study]] conducted on 517 rice [[landrace]]s revealed 80 loci associated with several categories of agronomic performance, such as grain weight, [[amylose]] content, and [[drought tolerance]]. Many of the loci were previously uncharacterized.<ref>{{cite journal | vauthors = Huang X, Wei X, Sang T, Zhao Q, Feng Q, Zhao Y, Li C, Zhu C, Lu T, Zhang Z, Li M, Fan D, Guo Y, Wang A, Wang L, Deng L, Li W, Lu Y, Weng Q, Liu K, Huang T, Zhou T, Jing Y, Li W, Lin Z, Buckler ES, Qian Q, Zhang QF, Li J, Han B | title = Genome-wide association studies of 14 agronomic traits in rice landraces | journal = Nature Genetics | volume = 42 | issue = 11 | pages = 961β967 | date = November 2010 | pmid = 20972439 | doi = 10.1038/ng.695 | s2cid = 439442 }}</ref> Not only is this methodology powerful, it is also quick. Previous methods of identifying loci associated with agronomic performance required several generations of carefully monitored breeding of parent strains, a time-consuming effort that is unnecessary for comparative genomic studies.<ref>{{cite journal | vauthors = Morrell PL, Buckler ES, Ross-Ibarra J | title = Crop genomics: advances and applications | journal = Nature Reviews. Genetics | volume = 13 | issue = 2 | pages = 85β96 | date = December 2011 | pmid = 22207165 | doi = 10.1038/nrg3097 | s2cid = 13358998 }}</ref>
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