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Drug interaction
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=== Examples === Examples of herb-drug interactions include, but are not limited to: * St. John's wort affects the clearance of numerous drugs, including [[cyclosporin]], [[SSRI]] antidepressants, [[digoxin]], [[indinavir]], and [[phenprocoumon]].<ref name="bjcp2" /> It may also interact with the anti-cancer drugs [[irinotecan]] and [[imatinib]].<ref name="oncologist2">{{cite journal|last1=Meijerman|first1=I.|last2=Beijnen|first2=J. H.|last3=Schellens|first3=J. H.M.|date=1 July 2006|title=Herb-Drug Interactions in Oncology: Focus on Mechanisms of Induction|journal=The Oncologist|volume=11|issue=7|pages=742β752|doi=10.1634/theoncologist.11-7-742|pmid=16880233}}</ref> * [[Salvia miltiorrhiza]] may enhance anticoagulation and bleeding among people taking warfarin.<ref name="drugs2" /> * [[Allium sativum]] has been found to decrease the plasma concentration of [[saquinavir]], and may cause [[hypoglycemia]] when taken with [[chlorpropamide]].<ref name="drugs2" /> * [[Ginkgo biloba]] can cause bleeding when combined with warfarin or [[aspirin]].<ref name="drugs2" /> * Concomitant [[Ephedra (medicine)|Ephedra]] and [[caffeine]] use has been reported to, in rare cases, cause fatalities.<ref>{{cite journal|last1=Ulbricht|first1=C.|last2=Chao|first2=W.|last3=Costa|first3=D.|last4=Rusie-Seamon|first4=E.|last5=Weissner|first5=W.|last6=Woods|first6=J.|date=1 December 2008|title=Clinical Evidence of Herb-Drug Interactions: A Systematic Review by the Natural Standard Research Collaboration|journal=Current Drug Metabolism|volume=9|issue=10|pages=1063β1120|doi=10.2174/138920008786927785|pmid=19075623}}</ref>
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