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Lactose intolerance
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=== Dietary avoidance === The primary way of managing the symptoms of lactose intolerance is to limit the intake of lactose to a level that can be tolerated.<ref name="NHS2016">{{cite web|url=http://www.nhs.uk/Conditions/lactose-intolerance/Pages/Treatment.aspx|title=Lactose intolerance - Treatment|website=NHS UK|access-date=11 August 2017|url-status=live|archive-url=https://web.archive.org/web/20170718135858/http://www.nhs.uk/Conditions/lactose-intolerance/Pages/Treatment.aspx|archive-date=18 July 2017}}</ref> Lactase deficient individuals vary in the amount of lactose they can tolerate,<ref name=NIH2014Dig/> and some report that their tolerance varies over time, depending on health status and pregnancy.<ref>{{Emedicine|med|3429|Lactose Intolerance}} Roy, Barakat, Nwakakwa, Shojamanesh, Khurana, July 5, 2006</ref><ref name="Szilagyi2015">{{cite journal | vauthors = Szilagyi A | title = Adaptation to Lactose in Lactase Non Persistent People: Effects on Intolerance and the Relationship between Dairy Food Consumption and {{sic|Evalu|tion|nolink=y}} of Diseases | journal = Nutrients | volume = 7 | issue = 8 | pages = 6751β79 | date = August 2015 | pmid = 26287234 | pmc = 4555148 | doi = 10.3390/nu7085309 | type = Review | doi-access = free }}</ref> However, as a rule of thumb, people with primary lactase deficiency and no small intestine injury are usually able to consume at least 12 grams of lactose per sitting without symptoms, or with only mild symptoms, with greater amounts tolerated if consumed with a meal or throughout the day.<ref name="NIH2014Dig" /><ref name="Szilagyi2015" /><ref name="SilanikoveLeitner2015">{{cite journal | vauthors = Silanikove N, Leitner G, Merin U | title = The Interrelationships between Lactose Intolerance and the Modern Dairy Industry: Global Perspectives in Evolutional and Historical Backgrounds | journal = Nutrients | volume = 7 | issue = 9 | pages = 7312β31 | date = August 2015 | pmid = 26404364 | pmc = 4586535 | doi = 10.3390/nu7095340 | type = Review | doi-access = free }}</ref> {| class="wikitable floatright sortable" style="text-align:right" |+'''Typical lactose levels in dairy products<ref name=gastroau>{{cite web|url=http://www.gastro.net.au/diets/lactose.html|title=Diet for Lactose Intolerance|url-status=live|archive-url=https://web.archive.org/web/20051224060911/http://www.gastro.net.au/diets/lactose.html|archive-date=2005-12-24}}</ref>''' ! Dairy product !! Serving<br /> size !! Lactose<br /> content !! Fraction |- |{{left}} Milk, regular | 250 ml(g) | 12 g | 4.8%{{0}} |- |{{left}} Milk, reduced fat | 250 ml(g) | 13 g | 5.2%{{0}} |- |{{left}} Yogurt, plain, regular | 200 g | 9 g | 4.5%{{0}} |- |{{left}} Yogurt, plain, low-fat | 200 g | 12 g | 6.0%{{0}} |- |{{left}} Cheddar cheese | 30 g | 0.02 g | 0.07% |- |{{left}} Cottage cheese | 30 g | 0.1 g | 0.33% |- |{{left}} Butter | 5 g | 0.03 g | 0.6%{{0}} |- |{{left}} Ice cream | 50 g | 3 g | 6.0%{{0}} |} Lactose is found primarily in [[dairy product]]s, which vary in the amount of lactose they contain: * '''Milk''' β unprocessed cow's milk is about 4.7% lactose; [[goat milk|goat's milk]] 4.7%;<ref>{{cite web|url=http://www.goatworld.com/articles/goatmilk/colostrum.shtml|title=Composition of Human, Cow, and Goat Milks|work=GoatWorld.com|first=Harold|last=Eddleman|date=25 December 2003|url-status=live|archive-url=https://web.archive.org/web/20070928192428/http://www.goatworld.com/articles/goatmilk/colostrum.shtml|archive-date=28 September 2007}}</ref> [[Sheep milk|sheep's milk]] 4.7%;<ref>{{cite web|url= https://www.food-intolerance-network.com/food-intolerances/lactose-intolerance/tables-of-lactose-content.html|title= Amount of Lactose in Milk Products|date= 21 November 2013|website= food-intolerance-network.com|publisher= Food Intolerance Network|access-date= 7 September 2017|url-status= live|archive-url= https://web.archive.org/web/20170907213920/https://www.food-intolerance-network.com/food-intolerances/lactose-intolerance/tables-of-lactose-content.html|archive-date= 7 September 2017}}</ref> [[buffalo milk]] 4.86%;<ref name="Peeva">{{cite journal|author=Peeva|year=2001|title=Composition of buffalo milk. Sources of specific effects on the separate components|url=http://bjas.hit.bg/07/693A.htm|journal=Bulgarian Journal of Agricultural Science|volume=7|pages=329β35|url-status=dead|archive-url=https://web.archive.org/web/20070829232522/http://bjas.hit.bg/07/693A.htm|archive-date=2007-08-29}}</ref> and [[Domestic yak|yak milk]] 4.93%.<ref>{{cite journal|vauthors=Jiang XP, Liu GQ, Wang C, Mao YJ, Xiong YZ|title=Milk trait heritability and correlation with heterozygosity in yak|journal=Journal of Applied Genetics|volume=45|issue=2|date=2004|pmid=15131352|pages=215β24|url=http://jag.igr.poznan.pl/2004-Volume-45/2/pdf/2004_Volume_45_2-215-224.pdf|archive-url=https://web.archive.org/web/20080307083908/http://jag.igr.poznan.pl/2004-Volume-45/2/pdf/2004_Volume_45_2-215-224.pdf|archive-date=2008-03-07|url-status=live}}</ref> * '''Sour cream''' and '''buttermilk''' β if made in the traditional way, this may be tolerable, but most modern brands add milk solids.<ref>{{cite journal|vauthors=Reger JV, Combs WB, Coulter ST, Koch RB |date=February 1, 1951|title=A Comparison of Dry Sweet Cream Buttermilk and Non-Fat Dry Milk Solids in Breadmaking|url=https://www.journalofdairyscience.org/article/S0022-0302(51)91682-7/abstract|journal=Journal of Dairy Science|volume=34|issue=2|pages=136β44|doi=10.3168/jds.S0022-0302(51)91682-7|doi-access=free}}</ref> * '''Yogurt''' β [[Lactobacillus acidophilus|lactobacilli]] used in the production of [[yogurt]] metabolize lactose to varying degrees, depending on the type of yogurt.<ref>{{cite web |first=Sharon |last=Perkins |date=19 November 2018 |publisher=SFGATE |url=http://healthyeating.sfgate.com/can-lactose-intolerant-eat-yogurt-aged-cheese-6130.html|title=Can a Lactose Intolerant Eat Some Yogurt & Aged Cheese?|url-status=live|archive-url=https://web.archive.org/web/20150428164624/http://healthyeating.sfgate.com/can-lactose-intolerant-eat-yogurt-aged-cheese-6130.html|archive-date=2015-04-28}}</ref> Some bacteria found in yogurt also produce their own [[lactase]], which facilitates digestion in the intestines of lactose intolerant individuals.<ref name="SilanikoveLeitner2015" /> * '''Cheese''' β The [[curdling]] of cheese concentrates most of the lactose from milk into the [[whey]]: fresh [[cottage cheese]] contains 7% of the lactose found in an equivalent mass of milk.<ref name=gastroau/> Further fermentation and [[Cheese ripening|aging]] converts the remaining lactose into [[lactic acid]]; traditionally made [[hard cheese]]s, which have a long ripening period, contain virtually no lactose:<ref name=ilovecheese>{{cite web|url=http://www.ilovecheese.com/lactose_intolerant_faqs.asp|title=Dairy Good: Home|url-status=live|archive-url=https://web.archive.org/web/20130730190352/http://www.ilovecheese.com/lactose_intolerant_faqs.asp|archive-date=2013-07-30}}</ref> cheddar contains less than 1.5% of the lactose found in an equivalent mass of milk.<ref name=gastroau/> However, manufactured cheeses may be produced using processes that do not have the same lactose-reducing properties.<ref>{{cite journal |last1=Muthukummarappan |first1=K |last2=Biswas |first2=A.C. |last3=Metzger |first3=L.E. |last4=Kapoor |first4=R |title=Effect of Natural Cheese Characteristics on Process Cheese Properties |url=https://www.journalofdairyscience.org/article/S0022-0302(07)71648-X/fulltext |journal=Journal of Dairy Science |year=2007 |volume=90 |issue=4 |pages=1625β1634 |publisher=Plum X Metrics |doi=10.3168/jds.2006-746 |pmid=17369202 |s2cid=32630538 |access-date=April 19, 2022|doi-access=free }}</ref> There used to be<ref name=Portnoy>{{cite journal |last1=Portnoy |first1=Matilde |last2=Barbano |first2=David M. |title=Lactose: Use, measurement, and expression of results |journal=Journal of Dairy Science |date=July 2021 |volume=104 |issue=7 |pages=8314β8325 |doi=10.3168/jds.2020-18706|pmid=33814136 |doi-access=free }}</ref> a lack of standardization on how lactose is measured and reported in food. The different molecular weights of anhydrous lactose or lactose monohydrate result in up to 5% difference.<ref>{{cite web|url=http://drinc.ucdavis.edu/goat1.htm|title=Goat Dairy Foods|url-status=dead|archive-url=https://web.archive.org/web/20071111141237/http://drinc.ucdavis.edu/goat1.htm|archive-date=2007-11-11|access-date=2007-10-11}}</ref> One source recommends using the "carbohydrates" or "sugars" part of the nutritional label as surrogate for lactose content,<ref name=ilovecheese/> but such "lactose by difference" values are not assured to correspond to real lactose content.<ref name=Portnoy/> The stated dairy content of a product also varies according to manufacturing processes and labelling practices, and commercial terminology varies between languages and regions.<ref name="Berdanier" /> As a result, absolute figures for the amount of lactose consumed (by weight) may not be very reliable. [[Kosher]] products labeled ''[[pareve]]'' or ''[[fleishig]]'' are free of milk. However, if a "D" (for "dairy") is present next to the circled "K", "U", or other ''[[hechsher]]'', the food product likely contains milk solids,<ref name="OHSU">{{cite web|url=http://www.ohsu.edu/xd/health/health-information/topic-by-id.cfm?ContentTypeId=90&ContentId=P01696|title=General guidelines for milk allergy|publisher=Oregon Health & Science University|url-status=dead|archive-url=https://archive.today/20121212035247/http://www.ohsu.edu/xd/health/health-information/topic-by-id.cfm?ContentTypeId=90&ContentId=P01696|archive-date=2012-12-12}}</ref> although it may also simply indicate the product was produced on equipment shared with other products containing milk derivatives. Lactose is also a commercial [[food additive]] used for its texture, flavor, and adhesive qualities. It is found in additives labelled as [[casein]], [[Caseinase|caseinate]], [[whey]], [[lactoserum]], [[milk solids]], [[modified milk ingredients]], etc.{{Citation needed|date=August 2017}} As such, lactose is found in foods such as processed meats ([[sausage]]s/[[hot dog]]s, sliced meats, [[pΓ’tΓ©]]s),<ref name="OHSU" /> gravy stock powder, [[margarine]]s,<ref>{{cite web |title=Margarine Regulations |url=http://www.gov.ns.ca/JUST/REGULATIONS/regs/marge.htm |url-status=live |archive-url=https://web.archive.org/web/20071011202241/http://gov.ns.ca/JUST/REGULATIONS/regs/marge.htm |archive-date=2007-10-11 }}</ref> sliced [[bread]]s,<ref>{{cite web |title=Enriched White Bread in Canada |url=http://www.celiac.ca/Articles/PAB%20Enriching%20GF%20Foods.html |publisher=The Canadian Celiac Association |url-status=dead |archive-url=https://web.archive.org/web/20071203005124/http://www.celiac.ca/Articles/PAB%20Enriching%20GF%20Foods.html |archive-date=2007-12-03 |access-date=2007-10-11 }}</ref><ref>{{cite journal |title=Influence of Nonfat Dry Milk Solids on the Nutritive Value of Bread |journal=Journal of Dairy Science |date=December 1946 |volume=29 |issue=12 |pages=821β9 | last1 = Riggs | first1 = Lloyd K | last2 = Beaty | first2 = Annabel | last3 = Johnson | first3 = Arnold H |doi=10.3168/jds.S0022-0302(46)92546-5 |doi-access=free}}</ref> breakfast cereals, [[potato chip]]s,<ref name="Bartek">{{cite web |title=Bartek, food additive company |url=http://www.bartek.ca/pdfs/Applications/SavouryProducts/SavourySnackFoods/Savoury%20Snack%20Foods%20Alphabetical%20List%20of%20Product%20Names.pdf |url-status=dead |archive-url=https://web.archive.org/web/20081217083729/http://www.bartek.ca/pdfs/Applications/SavouryProducts/SavourySnackFoods/Savoury%20Snack%20Foods%20Alphabetical%20List%20of%20Product%20Names.pdf |archive-date=2008-12-17 |access-date=2007-10-11 }}</ref> [[Food processing|processed foods]], [[medication]]s, prepared meals, meal replacements (powders and bars), protein supplements (powders and bars), and even [[beer]]s in the [[milk stout]] style. Some barbecue sauces and liquid cheeses used in fast-food restaurants may also contain lactose. When dining out, carrying lactose intolerance cards that explain dietary restrictions in the local language can help communicate needs to restaurant staff.<ref name="AllergyFacts2">{{cite web |title=Allergen Card - Milk/Dairy |url=https://allergyfacts.org.au/shop/food-preparation-tools/allergen-cards/allergen-card-milk-dairy |access-date=16 July 2024 |website=Allergy & Anaphylaxis Australia}}</ref> Lactose is often used as the primary filler (main ingredient) in most prescription and non-prescription solid pill form medications, though product labeling seldom mentions the presence of 'lactose' or 'milk', and neither do product monograms provided to pharmacists, and most pharmacists are unaware of the very wide scale yet common use of lactose in such medications until they contact the supplier or manufacturer for verification.{{Citation needed|date=April 2015}}
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